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The 10 Best Gluten-Free American Restaurants in Central Business District

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By Gluten Free Eats' gluten-free community

Updated Jul 2025

01
Modern Market Eatery

Modern Market Eatery

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Accommodating

904 16th St Mall, Denver, CO 80202, USA

GF OptionsCasualPizza100% Gluten FreeLunchAmericanBreakfastAllergen FriendlyCoffeeDairy Free OptionsDeliveryDinnerKid FriendlyOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsBread ItemsDessertsSandwichesBrunchPet FriendlyRestaurant
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Conner Lyapunov

the food was pretty okay!! unfortunately they were out of all of their lemonades which was a bummer :( otherwise they’re good with gluten free accommodations (on pizza and and sandwiches)

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02
5280 Burger Bar

5280 Burger Bar

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Celiac friendly

500 16th St Mall Suite 160, Denver, CO 80202, USA

LunchDinnerOpen LateAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyDedicated GF FryerCeliac Friendly
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Cheryl Olson

Great options for those with food allergy issues. I ate here on several occasions and the staff excellently made accommodations for my Celiac (gluten and dairy free) needs. 5280 has a dedicated gluten free fryer, which is a game changer for those with Celiac. The french fries are amazing here and I ordered them nearly every time I visited. I called my picky eater friend who was meeting me in Denver and told him I found a place for the both of us, which is difficult to do. I plan to eat at 5280 every time I find myself in Denver.

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03
Stout Street Social

Stout Street Social

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Accommodating

1400 Stout St, Denver, CO 80202, USA

SushiCocktailsAmericanGF OptionsDairy Free OptionsDinnerKid FriendlyOpen Late NightLunchOutdoor SeatingTake AwayBurgersCiderFriesBreakfastBrunchDeliveryBar
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Everything we ordered was good. Service was friendly but slow. There was a big rush just after we arrived that they were not prepared for. Otherwise this was a solid place. Outdoor seating, gluten free options.

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04
Yard House

Yard House

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Accommodating

1555 Court Pl, Denver, CO 80202, USA

LunchDinnerBrunchOpen LateAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyVegetarianBar
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Greg Boyd

Yard house always does a great job. 16th street mall is a real pain right now though. They were also very accommodating for our gluten allergy

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05
Sam's No. 3

Sam's No. 3

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Gluten-free options

1500 Curtis Street, Denver, CO 80202, USA

BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayOutdoor SeatingKid Friendly
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Brigit Mclain

This restaurant brings the feel of an old school diner in both atmosphere and food. The portions are huge for the price and absolutely delicious. I have celiac so finding something on the menu was a little difficult so I opted for an "unburritoed burrito" (a breakfast burrito without a tortilla. They accommodated with ease and it was delicious.

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