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The 5 Best Gluten-Free American Restaurants in Downtown

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By Gluten Free Eats' gluten-free community

Updated Jun 2025

01
Mesh - Indianapolis

Mesh - Indianapolis

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725 Massachusetts Ave, Indianapolis, IN 46204, USA

LunchDinnerBrunchOpen LateAmericanDeliveryTake AwayOutdoor SeatingBar

A vibrant spot offering exquisite flavors, a diverse menu, and a cozy ambiance, perfect for a memorable dining experience.

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Alex Carter

Mesh is yet another Cunningham restaurant with excellent food, service, and ambiance. Had the coravina and peanut butter pie, both of which were exquisite. The coravina was a delightful blend of curry, pineapple, and coconut flavors balanced with savory and perfectly fried rice and roasted carrots. The peanut butter pie also was delicious, and the heavy flavor of the peanut butter was well balanced with cream. I also appreciate their range of gluten-free , vegetarian, and vegan options. Will definitely be coming here again!

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02
The Flatiron @ The Point on Penn

The Flatiron @ The Point on Penn

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605 N Pennsylvania St, Indianapolis, IN 46204, USA

DinnerOpen LateAmericanDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyRestaurant

Experience a memorable evening with a unique prohibition-era bar, fabulous wine, and tailored service that leaves a lasting impression.

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robert delorenzo

We had dinner at the Chefs table and it was outstanding! Chef Brown and his team were amazing, my wife is gluten-free and they adjusted without compromising. From wine selection to proper portion sizing it was an evening we won't soon forget. Ask for a tour after dinner, there is a real prohibition Era bar in the basement.

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03
Bluebeard

Bluebeard

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653 Virginia Ave, Indianapolis, IN 46203, USA

LunchDinnerBrunchItalianAmericanCocktailsDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurantPet Friendly
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Patrick Kaufman

This place is Overrated. I grew up in "hipster central" Portland, OR in the 90's. This place is trying too hard. The beet salad was amazing and a healthy portion. Everything else was small portions. Our waiter was attentive but had almost too much energy. The menu had no congruence. I'm sure there are marvelous dishes here but way, way overpriced for Indy. Good attention to my friends celiac dietary needs. The amazing giant beet salad and their understanding of serious gluten free needs is why I gave it 4 stars instead of 3.

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04
Love Handle

Love Handle

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877 Massachusetts Ave, Indianapolis, IN 46204, USA

BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayKid FriendlyRestaurant
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Joey Smith

Went with my best friend a couple of weeks ago. First time there and they even have food that is gluten free if you require modified dishes. Highly recommend and will definitely return!

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05
Tavern On South

Tavern On South

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423 W South St, Indianapolis, IN 46225, USA

LunchDinnerAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyBar
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Lydia Courtright

They have a gluten free meal which made our decision to try it out easy. Service was great, food was just okay. What I will say is their homemade blue cheese dressing was certainly the best part. Had a filet that didn’t knock my socks off. $40 for a steak and a cocktail, could probably pass next time.

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