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The 13 Best Gluten-Free Spots Open Late in Downtown Des Moines

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By Gluten Free Eats' gluten-free community

Updated Jun 2025

01
Fresko

Fresko

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Celiac friendly

909 Locust St Ste. 103, Des Moines, IA 50309, USA

CocktailsBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerKid FriendlyOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBread ItemsBurgersDessertsSandwichesTacosCeliac FriendlyRestaurant

With a modern vibe and unique specials, this Des Moines hotspot is perfect for everything from brunch to celebrations, delivering consistently good experiences.

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Mijo Martinez (Mijo Martinez)

My chicken chiabatta sandwich was a bit dry and the food selection was limited, but they did have substantial gluten free options. The setting and staff were very nice, making it an overall excellent experience.

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02
Fong's Pizza

Fong's Pizza

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Accommodating

223 4th St, Des Moines, IA 50309, USA

LunchDinnerOpen LatePizzaDeliveryTake AwayKid FriendlyPet Friendly

This lively spot offers a variety of unique specialty pizzas and delicious drinks, making it a popular choice for a fun night out.

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Jenna Bug

I adore this place! The new location is superb. The drivers are kind and funny and the new menu updates are very tasty! I'm gluten free and have had zero issues.

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03
Americana

Americana

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Celiac friendly

1312 Locust St, Des Moines, IA 50309, USA

AmericanBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerCiderDessertsCeliac FriendlyKnowledgeable StaffKid FriendlyPancakesBread ItemsSandwichesCocktails

A lively spot with a vast menu and unique stations, perfect for groups but challenging for those with mobility issues due to stair access.

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Jennifer VanSickle

Love it every time. Good atmosphere and I'm pretty find if the gluten sensitive choices. Well worth it.

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04
Buzzard Billy’s

Buzzard Billy’s

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Accommodating

615 3rd St, Des Moines, IA 50309, USA

AmericanGF OptionsDinnerKid FriendlyOpen Late NightLunchTake AwayBread ItemsCiderBreakfastBrunchDeliveryOutdoor SeatingRestaurant

Unexpectedly fun spot with a lively, sports bar vibe, plus a standout cocktail selection and a variety of delicious menu options.

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Cortez Jones

Had the BEST experience here. Trying to find a restaurant that offers a gluten free menu as well as regular with no discernible differences in taste is 1 in a million and buzzard Billy’s is exactly that. Any time we ever come back it will be good at BB. Kristen, Kela and shiree are the best servers EVER!

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Dedicated gluten-free menu
05
Blaze Pizza

Blaze Pizza

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Accommodating

300 W Martin Luther King Jr Pkwy, Des Moines, IA 50309, USA

LunchDinnerOpen LatePizzaDeliveryTake AwayOutdoor SeatingKid Friendly
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