Top 9 Gluten-Free Italian Spots to Delight in Sioux Falls

Your curated guide to gluten-free dining options, with detailed reviews and recommendations for safe celiac-friendly meals.

MacKenzie River Pizza, Grill & Pub

120 W 11th St, Sioux Falls, SD 57104, USA
Gluten Free IconCeliac friendly
AmericanDeliveryDinnerKid FriendlyLunchOutdoor SeatingTake AwayVegetarian OptionsVegan OptionsPizzaItalianOpen LatePet Friendly
Chill vibes and a relaxed atmosphere make this spot a go-to for families, with a menu that keeps folks coming back year after year.

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Janet Fernandes
Janet Fernandes
There were plenty of gluten-free options. The salads were fresh but small for a meal. The flat breads were plenty to share, staff was friendly, but service was slow.

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Dedicated gluten-free menu

Maribella Ristorante

360 S Main Ave, Sioux Falls, SD 57104, USA
Gluten Free IconCeliac friendly
CocktailsItalianDinnerKid FriendlyOpen Late NightLunchOutdoor SeatingTake AwayVegetarian OptionsVegan OptionsDedicated GF Kitchen SpaceDessertsPastaPizzaDeliveryPet Friendly
A charming dining spot with a rich history and homemade pasta that leaves a lasting impression; a must-visit for unique flavors and warm hospitality.

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Emily Abele
Emily Abele
Was recommended by friends and saw it was highly rated on Google and Find me Gluten Free so had to check it out! Called ahead and was able to get a reservation in the bar area on a Saturday evening within 30 minutes. Ended up showing up early and they were able to seat us early! Attentive staff who were very knowledgeable about the entire menu. Definitely was more upscale than we were expecting but everyone was great and the food was phenomenal! Plan to return for a special occasion!

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Gluten-free options are marked

Johnny Carino's

2310 S Louise Ave, Sioux Falls, SD 57106, USA
Gluten-free options
LunchDinnerBrunchOpen LateItalianDeliveryTake AwayKid FriendlyRestaurant
A vibrant spot with a lively atmosphere and a diverse menu, though the music can get a bit loud at times.

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Bambi Clark
Bambi Clark
Very disappointed. I ordered Alfredo fettucine with chicken on gluten free noodles and I was told the Alfredo is pre made with flour in it, WTH, the cooks don't know how to make Alfredo sauce. I will be skipping this restaurant in the future.

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R Wine Bar & Kitchen

322 E 8th St, Sioux Falls, SD 57103, USA
Gluten Free IconAccommodating Gluten-Free
ItalianDairy Free OptionsDinnerOpen Late NightLunchOutdoor SeatingVegan OptionsVegetarian OptionsBread ItemsDeliveryTake AwayPet FriendlyRestaurant
A charming spot with a lovely ambiance and live music, perfect for a leisurely date night, though be ready for a long wait.

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Nicole Madsen
Nicole Madsen
Beautiful atmosphere with wonderful live music. The gluten free noodles were splendid and chicken very moist. The only semi-negative part is that the service took quite awhile, from ordering, to getting our food, to getting the check, we had to wait a very long time in between and spent close to 3 hours there.

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Gluten-free options are marked

Papa Murphy's | Take 'N' Bake Pizza

6725 W 41st St, Sioux Falls, SD 57106, USA
Gluten-free options
LunchDinnerItalianPizzaDeliveryTake AwayKid FriendlyVegetarian
Offering a tasty take-and-bake experience, this spot stands out with fresh ingredients and options for various dietary preferences.

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Gary Crawford
Gary Crawford
So good! We ordered pizza for a birthday party from Papa Murphy's because they offered a gluten free option that we needed for one of the kids. Everyone was able to get what they wanted and now we're the cool parents!

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Papa Murphy's | Take 'N' Bake Pizza

1608 S Sycamore Ave, Sioux Falls, SD 57110, USA
Gluten-free options
LunchDinnerItalianPizzaDeliveryTake AwayKid FriendlyVegetarian

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Lucinda Lovestravel
Lucinda Lovestravel
Great concept. Order pizza ahead, pick it up in 10-15 minutes and bake it when convenient. I wish this chain was in my state. Tuesday special $10 pizza. Plus they have a rewards program. Good pizza, love the thin crust. GREAT garlic rolls. (they have these available in a refrigerated case to grab n go) Instructions on best way to cook it are included. They also offer a gluten free!

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Godfather's Pizza

5107 W 41st St, Sioux Falls, SD 57106, USA
Gluten-free options
LunchDinnerItalianPizzaDeliveryTake AwayKid FriendlyRestaurant

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Jess
Jess
It is hard to use the drive thru now with the new 41st St. Not a huge deal. Our daughter loves the gluten free pizza. No issues with cross contamination. Best taco pizza in town!

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Papa Murphy's | Take 'N' Bake Pizza

1200 E 57th St Unit 1, Sioux Falls, SD 57108, USA
Gluten-free options
LunchDinnerItalianPizzaDeliveryTake AwayKid FriendlyVegetarian

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E.M. Olsen
E.M. Olsen
Pleasant staff and promptly made our order. The gluten free pizza crust was pretty good!

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Papa Murphy's | Take 'N' Bake Pizza

2101 W 41st St Suite 28, Sioux Falls, SD 57105, USA
Gluten-free options
LunchDinnerItalianPizzaDeliveryTake AwayKid FriendlyVegetarian

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Kay Koch
Kay Koch
Always a good bet but I wish the very small gluten free pizza wasn't so expensive. $18 for a small seems a bit steep.

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