Top 31 Gluten-Free Lunch Spots to Delight in Florence

Your curated guide to gluten-free dining options, with detailed reviews and recommendations for safe celiac-friendly meals.

Mellow Mushroom Florence

120 Dunbarton Dr, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerVeganOpen LatePizzaDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyBread ItemsRestaurant
Enjoy a laid-back vibe with a variety of tasty pizza options, perfect for customizing your own unique creation.

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Vicki Elmore
Vicki Elmore
Elmo is always my server. She always does an excellent job. She makes sure I get gluten free options.

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Eliza's Vegan Café

1832b W Lucas St, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerVeganDeliveryTake AwayOutdoor SeatingKid Friendly
Discover a hidden gem in rural SC, where mouthwatering vegan dishes and a cozy atmosphere create an unforgettable dining experience.

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Nel Husband
Nel Husband
This cafe is simply exceptional. Thank goodness for the sign on US151, or I would never have known to stop by. The last thing I expected in rural SC was an outstanding vegan meal. Without question, the best vegan burger I’ve ever had. The best vegan and gluten-free burger bun I’ve ever had! Soft! Beautiful-tasting! And the burger itself? Bloody incredible. The special sauce was the kicker. Everything about this burger was uber delicious. The fries were excellent as well - perfect size, perfect handcooked taste. The meal was so large I could have taken some back to the truck with me but I wanted to eat it all in the restaurant because I just loved being there. A very safe place for trans people 🏳️‍⚧️Great music!! Wonderful, wise messages on the wall from the cafe’s namesake, Eliza Jenkins. Her granddaughter Markeyshi, the owner (pictured), and her talented cook gave me such a warm welcome and a restaurant experience that I will always remember. Thank you so much 🧡 Worth driving for from Montana. Worth travelling from Aotearoa NZ 🇳🇿 for, for that matter! Giving Eliza’s a 500-star recommendation. Hope I can return very 🔜

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Buddy's

2519b W Palmetto St, Florence, SC 29501, USA
Gluten Free IconCeliac friendly
LunchDinnerDairy FreeVeganVegetarianBread ItemsBurgersKid FriendlyTake AwayPet FriendlyOutdoor SeatingBreakfastRestaurantDedicated GF Fryer
This spot has a fantastic atmosphere and is a hidden gem for travelers, promising great experiences and friendly vibes all around.

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Leslie Young
Leslie Young
Great food. Great people. Loved the gluten free bun option. Kids loved it. Will definitely be back next time we travel south!

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Olive Garden Italian Restaurant

2901 W Radio Dr, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerItalianMediterraneanDeliveryTake AwayKid Friendly
Known for its wonderful variety of salads and delicious sauces, this spot has some standout offerings that keep patrons coming back for more.

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Lewis rich
Lewis rich
The gluten-free pasta was great I had the mushroom sauce absolutely wonderful

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Gluten-free options are marked

King Jefe Taco and Sushi Bar

134 S Irby St, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerMexicanDeliveryTake AwayKid Friendly

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Koba Lyle
Koba Lyle
Fresh food, well made, clean. Like the Vegan, Gluten Free, and Oil Free options. Hope to see more. Very relaxed and well mannered staff.

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Wholly Smokin’

150 S Dargan St, Florence, SC 29506, USA
Gluten-free options
LunchDinnerBrunchDeliveryTake AwayOutdoor SeatingKid FriendlyBar

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D B
D B
A quaint renovated/ remodeled restaurant with stocked bar including gluten-free ciders.

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Firehouse Subs Florence

1925 Mountain Laurel Ct, Florence, SC 29505, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items
The spot features unique firefighter memorabilia and a cool vibe, perfect for customizing your next favorite sandwich.

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Dj Sullivan
Dj Sullivan
This was our first time eating at a Firehouse Subs. Really cool place a lot of firefighter memorabilia, and they dressed up the inside real nice. There's about 12 to 15 different subs you can get, and then you can custom make whatever you would like. For bread options, they have white wheat and gluten-free. I opted for the firefighter sub, which had roast beef ham and turkey on it, and I got it on wheat. It was absolutely one of the best subs I've ever had. They have a pepper sauce that is like a mild barbecue sauce, and you have got to try it. It was phenomenal. My wife opted for the turkey club, and she said hers was excellent as well. I would definitely stop into one of these again if I was near it

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Jersey Mike's Subs

2100 W Lucas St, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
DinnerGrab & GoKid FriendlyLunchTake AwayVegetarian OptionsVegan OptionsBread ItemsSandwichesDeliveryPet Friendly
A clean and well-lit spot with attentive staff ensuring a safe experience, perfect for a convenient pit stop on I-95.

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Michael Bredin
Michael Bredin
Accommodated Celiac gluten free sub well, cleaned slicer, all 3 employees changed gloves, brought out lettuce from the back. Had UDI gf buns and UDI gf snickerdoodle cookies. Clean bathrooms. Good stop off I-95. I tipped well; they did a good job.

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Gluten-free options are marked

Red Bowl Asian Bistro

2417 David H McLeod Blvd, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
SushiAsianDairy Free OptionsDeliveryDinnerKid FriendlyOpen Late NightLunchOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsPet FriendlyRestaurant
Enjoy a lovely atmosphere where you can customize your meal to suit your needs, all while savoring standout dishes like egg drop soup.

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megan h
megan h
As a person with highly symtomatic Celiac disease this was a great experience for me. Most things can be modified for gluten free. EXCELLENT egg drop soup!

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Dedicated gluten-free menu

Ruby Tuesday

1812 W Lucas St, Florence, SC 29501, USA
Gluten-free options
AmericanDinnerKid FriendlyOpen Late NightSeafoodLunchBrunchDeliveryTake Away
Fresh salad options are available, making it easy to create a healthy lunch on the go, but some orders can be overlooked.

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Michael Asaro
Michael Asaro
Sometimes it's hard to eat healthy while traveling, so I was glad to eat some salad for lunch from the salad bar. All the ingredients looked pretty fresh, and it was easy to make a salad that was gluten free.

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Flavors Of India

137 E Palmetto St, Florence, SC 29506, USA
Gluten-free options
BreakfastLunchDinnerBrunchDeliveryTake AwayKid FriendlyIndianRestaurant
Known for its delicious vegan options, this spot is a local favorite that always hits the mark for takeout and casual dining vibes.

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j o
j o
Great staff and excellent food!! Able to great Gluten Free meals! Love it so much, I get an order to go for dinner.

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SC Real Foods

1225 Celebration Blvd, Florence, SC 29501, USA
Gluten-free options
BreakfastLunchDinnerBakeryCafeDeliveryTake AwayKid FriendlyRestaurant

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Brenda Seller
Brenda Seller
We are from NY and we hunt for organic options while traveling, which is sometimes impossible. This is a GEM! I had the burger with caramelized onions and hand cut potatoes and it was delicious. There are organic and gluten free options. The white bean chili was incredible. I met the owner who cares about the quality of food she offered. I also bought 4 unique jellies in a gorgeous French collectable glass. It is also called "Peck Away Cafe". Will be back!

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Jersey Mike's Subs

110 Woody Jones Blvd Suite A, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyBread ItemsGrab & Go
Youthful vibe with mixed service experiences; cleanliness and order efficiency need improvement, but there's a dedicated area for unique dietary needs.

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Jessica G.
Jessica G.
This is an update. I went here last night and there was a bunch of younger people working. One was super friendly but kept screwing up our order. The girl who prepared the subs was a bit rude, didn't take my gluten allergy seriously, and just had an overall attitude that she could careless if she were there. The place was also not kept clean as customers came and went. They were also behind on online orders. I hope this changes because I like this location.

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Gluten-free options are marked


Tubb's Shrimp and Fish Co.

1500 2nd Loop Rd, Florence, SC 29505, USA
Gluten-free options
LunchDinnerSeafoodDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant

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Melissa Kirk
Melissa Kirk
Delicious and loved how helpful they were with a gluten free meal!

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Healthy Choice Cafe

531 W Evans St, Florence, SC 29501, USA
Gluten-free options
LunchDinnerVeganTake AwayPet FriendlyOutdoor SeatingKid Friendly

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Elizabeth Prince
Elizabeth Prince
Very pleasant staff. Great tasting fries. Homemade salmon Burger, very flavorful. Maybe offer a gluten free bun.

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Victors

126 W Evans St, Florence, SC 29501, USA
Gluten-free options
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayFrenchOutdoor SeatingKid FriendlyBarRestaurantPet Friendly

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Leigh Frame
Leigh Frame
Delicious and gluten free friendly. Great service.

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Outback Steakhouse

110 Dunbarton Dr, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateDeliveryTake AwayKid FriendlyBarRestaurant

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bjwyndham
bjwyndham
Usually do well with gluten allergy. One of the few restaurants in our area that offer GF.

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Dedicated gluten-free menu



IHOP

2699 David H McLeod Blvd, Florence, SC 29501, USA
Gluten-free options
BreakfastLunchDinnerBrunchDeliveryTake AwayKid Friendly

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Sara Bennetts
Sara Bennetts
DIL on gluten free diet. It was her birthday and her choice was pancakes for supper. The waiter served all of our meals and waited until then to tell DIL they were out of gluten free batter . We would've have never gone to IHOP if it wasn't for the availability of something for her to eat and enjoy.

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Chick-fil-A

2705 David H McLeod Blvd, Florence, SC 29501, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerGrab & GoDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly

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Michelle Christian
Michelle Christian
You just can never go wrong with chickfila. So many gluten free options!

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Freddy's Frozen Custard & Steakburgers

1104 Pamplico Hwy, Florence, SC 29505, USA
Gluten-free options
LunchDinnerGrab & GoDeliveryTake AwayOutdoor SeatingKid FriendlyOpen LateBurgersPet FriendlyRestaurant

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Aner Jackson
Aner Jackson
I am Gluten free I can eat there...

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LilJazZi's

163 N Dargan St, Florence, SC 29506, USA
Gluten-free options
BreakfastLunchDinnerBrunchAmericanDeliveryOutdoor SeatingKid Friendly
A cozy spot with rave reviews, perfect for a delightful breakfast experience and known for its warm hospitality.

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Deborah Weisz-Van Orden
Deborah Weisz-Van Orden
We had a wonderful breakfast here. Traveling through for the holidays and read the great reviews, which are all true, and decided to experience it for ourselves. Highly recommend the platter! And if you are gluten intolerant, as I am, the owner offered some nice options. The owner is just lovely, and so welcoming! Highly recommend this place!!!

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Green Leaf Cafe @Mcleod Fitness Center

2437 Willwood Dr, Florence, SC 29501, USA
Gluten-free options
LunchCafeDeliveryKid FriendlyRestaurant
Known for its phenomenal veggie burger and customizable protein bowls, this spot offers a great variety of drinks and smoothies to enjoy.

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Gary W.
Gary W.
This is my new favorite spot for healthy cuisine. The Phenomenal Burger is titled quite accurately. As someone who struggles to find gluten-free dishes when eating out, this burger delivers. It's a veggie burger on gluten-free pita bread with your choice of toppings. I was stuck on this sandwich for weeks. I had to make myself try something else. The Protein Bowl is delicious. I also had this prepared with the veggie patty instead of the choices of chicken, salmon, or shrimp. You choose your vegetables and sauce to go with it. The staff is very friendly and actually want to know what you think of the food. I almost forgot, they have a fantastic selection of drinks and smoothies to go with your meal or to enjoy on their own. Enjoy!

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