Top 8 Gluten-Free Sandwich Spots to Delight in Charleston

Your curated guide to gluten-free dining options, with detailed reviews and recommendations for safe celiac-friendly meals.

Annie O' Love's Cookie Cafe

1901 Ashley River Rd, Charleston, SC 29407, USA
Gluten Free Icon100% Dedicated Gluten-Free
Vegan OptionsAllergen FriendlyBakeryBreakfastBrunchCoffeeDairy Free OptionsDeliveryDinnerKid FriendlyLunchTake AwayVegetarian OptionsKnowledgeable StaffBread ItemsDessertsSandwichesWaffles / Crepes100% GFSeparate GF MenuDedicated GF Kitchen SpacePancakesPet Friendly
Experience a vibrant atmosphere with inventive vegan creations that surprise and delight, making it a must-visit spot for anyone nearby.

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Nautia Symonne
Nautia Symonne
One of the few, if not only gluten free and vegan restaurants in the area. I will definitely be back. My pesto sandwich was awesome. The cookies are a hit too 🙌🏿

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Dedicated gluten-free menu

Heavy's Barburger

1137 Morrison Dr, Charleston, SC 29403, USA
Gluten Free IconCeliac friendly
LunchDinnerDairy FreeAllergen FriendlyVeganVegetarianDedicated GF FryerTake AwayBread ItemsBurgersFriesSandwichesBeerKid FriendlyOutdoor SeatingCasualPet FriendlyDessertsCocktailsDeliveryRestaurantOpen LateBar
A chill burger spot with ample parking, quick service, and tasty smash-style patties that impress burger lovers of all kinds.

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Dan Rose
Dan Rose
Celiac review here. Food is delicious American fare. Smashed burger gluten free and gf fries both sweat potato and crinkle cut with dedicated fryer. Good sauces. Would go again.

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Dedicated gluten-free menu

Brown Dog Deli

225 Calhoun St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
Allergen FriendlyDairy Free OptionsDeliveryKid FriendlyLunchOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsBread ItemsSandwichesAmericanBreakfastDinnerBrunchRestaurant
Charming spot with unique sandwiches, retro decor, and a laid-back vibe that's perfect for a relaxing lunch or casual hangout.

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Philip Mager
Philip Mager
Great sandwiches. Great atmosphere. Gluten free options are fantastic. Super friendly and helpful staff.

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Gluten-free options are not marked

East Bay Deli - Downtown

334 E Bay St Ste H, Charleston, SC 29401, USA
Gluten-free options
Salad BarLunchKid FriendlyBread ItemsSandwichesDeliveryTake AwayDessertsRestaurantBreakfast
A standout spot in the south with a wide variety of options, fast service, ample parking, and plenty of seating for a laid-back vibe.

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Billy Blake
Billy Blake
It's difficult to find great delis in the south, but this is definitely one of them. They offer a wide variety of options, including Gluten Free bread. They are open for lunch and early dinner, and there is ample parking available in front of the deli. Another great aspect is that they have plenty of seating. Overall, it's a fantastic deli that ticks all the boxes.

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Ruby Sunshine

171 E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsBrunchBreakfastKid FriendlyOutdoor SeatingTake AwayBread ItemsSandwichesBurgersLunchAmericanDeliveryPet Friendly
Dive into a vibrant breakfast scene with a diverse menu, speedy service, and some seriously delicious mimosas that keep everyone coming back!

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Amber Easterling
Amber Easterling
A must for breakfast or brunch! They have a gluten friendly menu if you ask. They have a dedicated cooking space and fryer for GF food and they offer GF bread for burgers/sandwiches. The French toast is amazing!!

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Jersey Mike's Subs

3875 W Ashley Cir Suite 410, Charleston, SC 29414, USA
Gluten-free options
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid FriendlyBread Items
Known for its tasty Phillysteaks and unique customization options, it’s a cozy spot, so ordering ahead is best to avoid the cramped waiting area.

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Neil & Heather Newman
Neil & Heather Newman
Phillysteak is great! Gluten Free Buns are tasty and they grilled up one of the Phillysteaks without onions and peppers special order. Next time would probably order ahead as waiting area is a bit cramped but staff were all great!

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Jersey Mike's Subs

1975 Magwood Dr Unit v, Charleston, SC 29414, USA
Gluten-free options
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid FriendlyBread Items
Experience attentive service and delicious offerings in a cozy spot that truly caters to special dietary needs.

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Lydia Poole
Lydia Poole
THANK YOU! it’s such a blessing to eat somewhere where they CARE about your gluten free need (due to allergy). so careful to make my sandwich so that it doesn’t make me sick! the food is great, staff is better!

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Legend Deli

41-A George St, Charleston, SC 29401, USA
Gluten-free options
BreakfastLunchBrunchSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread ItemsRestaurant

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Bobby (PapaT)
Bobby (PapaT)
The gluten free smash burger is great! No need for traditional ketchup and mustard. It doesn’t need it!

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