Top 17 Gluten-Free Dining Spots to Explore in Downtown Des Moines

615 3rd St, Des Moines, IA 50309, USA
Gluten Free IconAccommodating Gluten-Free
DeliveryKid FriendlyLunchTake AwayDinner
This lively spot offers a dedicated gluten-free menu with extensive, flavorful options, ensuring those with dietary needs can enjoy a Creole/American mix in a laid-back sports bar vibe. The welcoming atmosphere and attentive service make it a top choice for gluten-free dining.

People are saying
View more
Cortez Jones
Cortez Jones
Had the BEST experience here. Trying to find a restaurant that offers a gluten free menu as well as regular with no discernible differences in taste is 1 in a million and buzzard Billy’s is exactly that. Any time we ever come back it will be good at BB. Kristen, Kela and shiree are the best servers EVER!

Menu
View menu
Dedicated gluten-free menu

909 Locust St Ste. 103, Des Moines, IA 50309, USA
Gluten Free IconCeliac friendly
DeliveryKid FriendlyLunchTake AwayDinner
This spacious, modern venue impresses with its clean, well-designed interior and charming green glass accents, creating an upscale yet relaxed vibe. Known for its excellent gluten-free and vegan options, it offers a fun, relaxed atmosphere and wonderful service that makes dining enjoyable for all.

People are saying
View more
Mijo Martinez (Mijo Martinez)
Mijo Martinez (Mijo Martinez)
My chicken chiabatta sandwich was a bit dry and the food selection was limited, but they did have substantial gluten free options. The setting and staff were very nice, making it an overall excellent experience.

Menu
View menu
Gluten-free options are marked

300 W Martin Luther King Jr Pkwy Suite 120, Des Moines, Iowa, United States
Gluten Free IconAccommodating Gluten-Free
DeliveryKid FriendlyLunchTake AwayDinner
This lively eatery features a trendy, comfortable, semi-industrial decor with both indoor and outdoor seating, creating a fun, energetic, and upbeat atmosphere. The staff is extremely knowledgeable and helpful about gluten-free options, making it a go-to spot for gluten-free dining.

People are saying
View more
Brett Giberson
Brett Giberson
Great food! Excellent gluten free options. Awesome location. We will be back!

Menu
View menu
Dedicated gluten-free menu

300 SW 5th St, Des Moines, IA 50309, USA
Gluten-free options
DeliveryKid FriendlyLunchTake AwayDinner
This cafe offers a cool and hip atmosphere with a soundtrack featuring The Smiths, creating a vibrant setting. Known for exceptional gluten-free options and house-made gluten-free bread, it provides a welcoming space with free street parking and attentive service, ideal for gluten-free diners.

People are saying
View more
Deborah Kelly
Deborah Kelly

Menu
View menu

200 10th St, Des Moines, IA 50309, USA
Gluten-free options
DeliveryKid FriendlyLunchTake AwayDinner
This expansive Southern-style venue offers a relaxing atmosphere where conversations flow easily without shouting. The attentive service and great ambiance create a welcoming setting, complemented by a notable selection of gluten-free options ensuring a safe and enjoyable experience for gluten-sensitive guests.

People are saying
View more
Ben Miller
Ben Miller
Went in on a quiet Thursday afternoon and the service and food were top shelf. Ribeye steak was cooked to perfection. Brussels were excellent and the cornbread is actually GLUTEN FREE! Start with the deviled eggs or the street corn dip!

Menu
View menu

900 Mulberry St, Des Moines, Iowa, United States
Gluten-free options
DeliveryKid FriendlyLunchTake AwayDinner
This vibrant spot offers an upscale, hipster vibe with dim lighting and murals that create a unique atmosphere. The spacious outdoor patio invites gatherings, and the venue is known for being celiac friendly with clearly marked gluten-free options and sensitivity to cross-contamination, making it a great choice for gluten-free diners.

People are saying
View more
Jesse Graves
Jesse Graves

Menu
View menu

208 Court Ave, Des Moines, Iowa, United States
Gluten-free options
DeliveryLunchTake AwayDinnerRestaurant
This venue offers a quiet, intimate vibe downstairs and a classy, swanky atmosphere upstairs, perfect for those seeking reliable gluten-free dining. The excellent service enhances the experience, making it a standout choice for gluten-free guests.

People are saying
View more
Brian Moe
Brian Moe
Delicious food options. Had the gluten free steak and mushroom flatbread. It was hold-your-breath-and-close-your-eyes delicious. Brussel sprouts were on point. Deconstructed nachos were amazing. And service was excellent, especially given the unexpected rush at the end of the night.

Menu
View menu

1417 Walnut St, Des Moines, Iowa, United States
Gluten-free options
DeliveryLunchTake AwayDinnerRestaurant
Set in a tastefully renovated historic building, this spacious spot offers a friendly atmosphere with both indoor and outdoor seating enhanced by great lighting. The service and ambiance are great, making it a nice place to meet folks for lunch with gluten-free options available.

People are saying
View more
Alyssa Wang
Alyssa Wang

Menu
View menu

210 4th St, Des Moines, Iowa, United States
Gluten-free options
DeliveryKid FriendlyLunchTake AwayDinner
Step into an authentic English pub atmosphere with charming British decorations and an old back alley feel that transports you across the pond. The prime outdoor patio and cozy indoor seating create a great ambiance perfect for enjoying a well-curated selection of gluten-free beers and ciders.

People are saying
View more
Cory Zorn
Cory Zorn
Food sucked you need to pay attention to people that have food allergies all I could buy was a bowl of soup because everything else had bread in it the waitress said they'll take my croutons off guess what that's not gluten-free

Menu
View menu

200 4th St, Des Moines, Iowa, United States
Gluten Free IconAccommodating Gluten-Free
DeliveryKid FriendlyLunchTake AwayDinner
This cozy spot blends old and new architecture, creating a welcoming atmosphere with vintage touches reminiscent of an old hotel. While it offers gluten-free and vegan options, the experience highlights the importance of attentive service and a thoughtful setting for those with dietary needs.

People are saying
View more
Justyne Valentine
Justyne Valentine
So. I don’t even know where to begin. Pho was cold, vegan pho was very underwhelming and both it and the beef had a bitter aftertaste. The beef was ordered and charged as a full size, but was definitely in a smaller bowl than the vegan. I asked if one of the foods was able to be made gluten free and if they could find out which part wasn’t gluten free and they said they’d find out, walked to the counter, walked back, and told me they think ‘it all has it in it. or maybe just the sauce?’ We ordered a regular % cloud match boba and a 50% sweet Thai milk tea with oat milk. The cloud matcha came out with 50% sweet and the Thai milk tea came out with milk. Lastly, the vegan pho was specifically stated that it’s a wheat allergy and I found several egg noodles in it! I’m very allergic to dairy and wheat- both were stated when ordering every single thing- yet both ended up in my system! Not part of the review :if you think I’m just Karen-ing or whatever, please see my profile- I very very rarely post negatives reviews anywhere. This one is just so dangerous that it needs to be out there asap

Menu
View menu

1003 Locust St, Des Moines, Iowa, United States
Gluten-free options
DeliveryKid FriendlyLunchTake AwayDinner
This venue offers a lively yet upscale atmosphere with vintage flooring and dim lighting that evoke a European feel. Guests can enjoy their time on the patio for a relaxed dining experience, complemented by fun, expertly crafted cocktails in a vibrant setting.

People are saying
View more
Sparkies Sparkies
Sparkies Sparkies
If you are CELIAC, do NOT come here. They do not have gluten free options. On the opposite, they assured me cross contamination was guaranteed because vast majority of their menu has items with gluten.

Menu
View menu

1420 Locust St, Des Moines, Iowa, United States
Gluten-free options
DeliveryKid FriendlyTake AwayDinnerOutdoor Seating
This cozy French brasserie offers an elegant ambiance with soft lighting that complements its attentive service. The staff is well-informed about gluten-free needs, providing extra assurance for celiac diners in a bustling, authentic Parisian setting.

People are saying
View more
Jill Pointer
Jill Pointer

Menu
View menu

300 W Martin Luther King Jr Pkwy, Des Moines, Iowa, United States
Gluten-free options
DeliveryLunchTake AwayDinnerRestaurant
This eatery offers a highly customizable ordering process with a variety of bases like cauliflower rice and fresh proteins, ideal for gluten-free diners. The clean, spacious setting and quick, attentive service ensure a comfortable, safe dining experience for those with gluten sensitivities.

People are saying
View more
Karen Loomis
Karen Loomis

Menu
View menu

801 Grand Ave Suite 370, Des Moines, IA 50309, USA
Gluten-free options
DeliveryKid FriendlyLunchTake AwayRestaurant

People are saying
View more
Margret Stanley
Margret Stanley

Menu
View menu

655 Walnut St #219, Des Moines, Iowa, United States
Gluten-free options
DeliveryLunchTake AwayRestaurant

People are saying
View more
Esther Rodriguez
Esther Rodriguez

Menu
View menu

801 Grand Ave STE 200, Des Moines, Iowa, United States
Gluten-free options
DeliveryKid FriendlyTake AwayDinnerRestaurant
A vibrant spot known for its lively atmosphere, stunning decor, and exceptional service, though there may be occasional hiccups during busy times.

People are saying
View more
Michele Mosley
Michele Mosley

Menu
View menu

1303 Walnut St, Des Moines, Iowa, United States
Gluten-free options
DeliveryKid FriendlyLunchTake AwayDinner
Tucked away near downtown, this spot offers a quiet retreat with a lively yet cozy atmosphere and a huge patio perfect for relaxing. The wide array of drinks and plentiful mojito options complement the inviting setting, making it a great choice for those seeking a gluten-free friendly environment.

People are saying
View more
Jessie Arrellano
Jessie Arrellano

Menu
View menu

© 2025 Atly - Your Local Guide to Gluten-Free Dining