Top 35 Gluten-Free Spots Open Late to Enjoy in Des Moines

Your curated guide to gluten-free dining options, with detailed reviews and recommendations for safe celiac-friendly meals.

Louie's Wine Dive

4040 University Ave suite a, Des Moines, IA 50311, USA
Gluten Free IconCeliac friendly
Wine BarCocktailsAmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingSeafoodTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBeerOpen LateDeliveryPet FriendlyRestaurant
A favorite local spot with a vibrant patio and a diverse menu that keeps everyone happy, offering fun shareable bites and tasty drinks.

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Harv
Harv
This place is a gluten-free haven.

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Fresko

909 Locust St Ste. 103, Des Moines, IA 50309, USA
Gluten Free IconCeliac friendly
CocktailsBrunchAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerKid FriendlyOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBread ItemsBurgersDessertsSandwichesTacosRestaurant
With a modern vibe and unique specials, this Des Moines hotspot is perfect for everything from brunch to celebrations, delivering consistently good experiences.

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Mijo Martinez (Mijo Martinez)
Mijo Martinez (Mijo Martinez)
My chicken chiabatta sandwich was a bit dry and the food selection was limited, but they did have substantial gluten free options. The setting and staff were very nice, making it an overall excellent experience.

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Bar Nico

428 E Locust St, Des Moines, IA 50309, USA
Gluten Free Icon100% Dedicated Gluten-Free
MexicanCocktailsAllergen FriendlyDinnerOpen Late NightLunchTake AwayVegetarian OptionsVegan OptionsTacos100% GFSeparate GF MenuSeparate OvenKnowledgeable StaffDedicated GF Kitchen SpaceDessertsDedicated GF FryerBreakfastBrunchDeliveryPet FriendlyKid FriendlyOutdoor Seating
Experience a culinary gem with fresh, flavorful dishes, creative options, and top-notch cocktails in a vibrant setting that's perfect for any occasion.

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Emily Onomatopoeia
Emily Onomatopoeia
O.M.G. 100% gluten free kitchen AND the food was absolutely amazing!! Our waitress was super friendly! I would give more than 5 stars if I could!!!

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Dedicated gluten-free menu

Fong's Pizza

223 4th St, Des Moines, IA 50309, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LatePizzaDeliveryTake AwayKid FriendlyPet Friendly
This lively spot offers a variety of unique specialty pizzas and delicious drinks, making it a popular choice for a fun night out.

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Jenna Bug
Jenna Bug
I adore this place! The new location is superb. The drivers are kind and funny and the new menu updates are very tasty! I'm gluten free and have had zero issues.

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Americana

1312 Locust St, Des Moines, IA 50309, USA
Gluten Free IconCeliac friendly
AmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerCiderDessertsKnowledgeable StaffKid FriendlyPancakesBread ItemsSandwichesCocktails
A lively spot with a vast menu and unique stations, perfect for groups but challenging for those with mobility issues due to stair access.

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Jennifer VanSickle
Jennifer VanSickle
Love it every time. Good atmosphere and I'm pretty find if the gluten sensitive choices. Well worth it.

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Buzzard Billy’s

615 3rd St, Des Moines, IA 50309, USA
Gluten Free IconAccommodating Gluten-Free
AmericanDinnerKid FriendlyOpen Late NightLunchTake AwayBread ItemsCiderBreakfastBrunchDeliveryOutdoor SeatingRestaurant
Unexpectedly fun spot with a lively, sports bar vibe, plus a standout cocktail selection and a variety of delicious menu options.

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Cortez Jones
Cortez Jones
Had the BEST experience here. Trying to find a restaurant that offers a gluten free menu as well as regular with no discernible differences in taste is 1 in a million and buzzard Billy’s is exactly that. Any time we ever come back it will be good at BB. Kristen, Kela and shiree are the best servers EVER!

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Dedicated gluten-free menu

Eatery A

2932 Ingersoll Ave, Des Moines, IA 50312, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchOpen LateMediterraneanDeliveryTake AwayOutdoor SeatingKid Friendly
A hidden gem with a charming atmosphere, great happy hour deals, and a lovely patio, perfect for those seeking unique dining experiences.

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Hunter Gonzales
Hunter Gonzales
Food was delicious and decently priced, so many gluten free options. Service was quick and simple nice but not always checking up on you but consistent service overall. Kinda nosy but private as well. Definitely would come back as an outastater 👏

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Parlor

4041 Urbandale Ave, Des Moines, IA 50310, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchOpen LatePizzaDeliveryTake AwayOutdoor SeatingKid FriendlyPet Friendly
This spot boasts a fun, classy vibe with a cool aesthetic, and visits guarantee enjoyable experiences for a diverse crowd.

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Nicholas Kalianoff
Nicholas Kalianoff
Great place to sit on the patio or watch the games. Very conscious about gluten free options also. Good drinks, reasonable prices.

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Dirt Burger

407 E 5th St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerVeganOpen LateDeliveryTake AwayKid Friendly
Experience a mouthwatering, indulgent veggie burger packed with unique flavors and textures, plus incredible sides that steal the show!

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Michelle M.
Michelle M.
Amazing! Probably the best dang burger I've ever had... the lil' Elvis and the phenomenal dirt balls were the icing on the cake. Gluten-free bun also available. I'd rate this more than 5 stars if it was possible.

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F&O's / Felix and Oscars

4050 Merle Hay Rd, Des Moines, IA 50310, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateItalianPizzaDeliveryTake AwayKid FriendlyBrunch
With a secret menu and fantastic vibes, this spot is loved for its awesome choices and a fun atmosphere that keeps everyone entertained.

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Jamie Goff
Jamie Goff
Their Gluten Free pizza is amazing!!! Went to order it on door dash and it wasn't showing up so I called the restaurant and spoke to Emily and she went above and beyond to get me my gluten free pizza. Second time we've ordered from them and both times its been fantastic!! Even better when the customer Service rocks!!

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St. Kilda Cafe & Bakery

300 SW 5th St, Des Moines, IA 50309, USA
Gluten-free options
BreakfastLunchDinnerBrunchBakeryOpen LateCafeCocktailsDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
With a cozy atmosphere and stunning decor, this brunch spot serves up top-notch lattes and creative seasonal drinks that'll leave you impressed.

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Brooke Weber
Brooke Weber
I have been here several times recently for brunch. This place knows what they are doing and they are really good at it: the atmosphere, the decor, the food, the service. The lattes here are the best in the area, hands down. Even the cups and saucers are beautiful and add to my enjoyment of the coffee drinks. I want the exact cups for my own home. The seasonal latte flavors are creative and never overly sweet. I do love a pumpkin spice latte, and St. Kilda has the best. I was interested in a seasonal mocha and was hesitant to order it for fear it would be too sweet, but the server told me more about it so I decided to try it. It was the best mocha I’ve ever had with the perfect balance of flavors and just the right amount of sweetness. Everything that’s a part of the Big Aussie Breakfast is prepared to perfection: thick cut bacon, delicious blistered roasted tomatoes, perfectly crispy house-made bread. Even the gluten-free bread is excellent. Last week my boyfriend got a hashbrown on the side and it was the best hashbrown I’ve ever had - a lovely soft texture on the inside and perfectly crispy all the way around on the outside. The last 3 times I’ve eaten there, we’ve had the same server. I love her! Very friendly, relatable, and a bit quirky in the best possible way. After our last visit, I decided St. Kilda in Valley Junction is my favorite place for brunch.

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Northern Lights Pizza (102)

2558 Hubbell Ave, Des Moines, IA 50317, USA
Gluten-free options
LunchDinnerOpen LateItalianPizzaDeliveryTake AwayKid Friendly
Known for its excellent pickup and delivery service, this place stands out with its tasty options and commitment to community support.

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April Worrall
April Worrall
love the gluten-free options! Great food and a great company that gives back to our communities.

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Malo

900 Mulberry St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerBrunchOpen LateDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurantMexican
Experience a taco haven where fresh, handmade tortillas and savory portobello mushrooms steal the show, leaving you craving more.

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Gina W.
Gina W.
My first food stop in Iowa was to take a solo walk to get tacos at Malo. This one was a home run at my first at-bat as a Des Moines rookie. Wow. I timed it just right, and they were placing my bag of food on the table right as I walked in the door. I got the avocado and fried onions on corn tortillas, and instead of getting a combo, I got the portobello mushrooms as my side. That way I was able to just put them on my tacos. I also got a side of fruit with sweet chili sauce. It didn't want to have anything super spicy before my marathon (think about it) so I got the pico de gallo. The tacos were delicious, and the fresh tortillas seemed handmade. The fruit was so juicy and sweet, but the stunner here was the portobello mushroom - like steak strips. Savory and meaty but not too salty... Just amazing. I had enough left over for a second meal. Great vegan and gluten-free options.

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The Royal Mile

210 4th St, Des Moines, IA 50309, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LateDeliveryTake AwayOutdoor SeatingKid FriendlyBarRestaurantPet Friendly
Charming spot with a cozy vibe and British pub decor, plus an impressive drink selection for all tastes.

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Kyle Schmaltz
Kyle Schmaltz
Great place, it's nice they have gluten free options like salads available.

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RoCA

208 Court Ave, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerOpen LateAmericanCocktailsDeliveryTake AwayBarRestaurant
Perfect spot to kick back with unique cocktails and a rotating menu, especially before catching a show nearby!

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Brian Moe
Brian Moe
Delicious food options. Had the gluten free steak and mushroom flatbread. It was hold-your-breath-and-close-your-eyes delicious. Brussel sprouts were on point. Deconstructed nachos were amazing. And service was excellent, especially given the unexpected rush at the end of the night.

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Angry Goldfish Pub & Eatery

2301 SW 9th St, Des Moines, IA 50315, USA
Gluten-free options
LunchDinnerBrunchOpen LateDeliveryTake AwayOutdoor SeatingKid Friendly
Burgers shine here with awesome deals, a lively vibe, and a great selection that keeps everyone happy!

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Billie Newland (billiexnewland)
Billie Newland (billiexnewland)
Fun place with great food options! Love they do deals on their burgers and the fact they have gluten free buns available!

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Fuzzy's Taco Shop

300 W Martin Luther King Jr Pkwy Suite 120, Des Moines, IA 50309, USA
Gluten Free IconAccommodating Gluten-Free
MexicanLunchAllergen FriendlyBreakfastBrunchDinnerKid FriendlyOutdoor SeatingTake AwayTacosOpen LateDeliveryRestaurant
Enjoy a lively atmosphere with live music, plenty of space to relax, and a reputation for amazing, fresh dishes in a prime location.

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Brett Giberson
Brett Giberson
Great food! Excellent gluten free options. Awesome location. We will be back!

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Dedicated gluten-free menu

Truman's KC Pizza Tavern

400 SE 6th St, Des Moines, IA 50309, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LatePizzaDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
Unique pizza options and a fun atmosphere make this spot a must-visit, especially with an inviting patio for summer hangouts!

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Jeff King
Jeff King
The gluten-free pizza was decent. My wife said her burger rocked. It was the Frisco melt, and I had the pasta. It was a penne pasta with a southwest Alfredo sauce, plus chicken and tortilla strips. It was fantastic.

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Sakari Sushi Lounge

2605 Ingersoll Ave, Des Moines, IA 50312, USA
Gluten-free options
LunchDinnerOpen LateAsianSushiDeliveryTake AwayOutdoor SeatingKid FriendlyBar
With an excellent menu and well-labeled options, this lively spot offers a variety that keeps guests coming back for more.

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Allison Snyder
Allison Snyder
It was a little nosy but this place had an excellent menu and the pricing was good. Their gluten free options were well-labled and they had a good variety.

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Akebono 515

215 10th St Suite 120, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerOpen LateAsianDeliveryTake AwayOutdoor Seating
With phenomenal service and beautiful pottery, this spot is a must-visit for sushi lovers, though parking can be tricky.

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Sarah Greenfield
Sarah Greenfield
Phenomenal service every time I go. I hate tofu but I am a fan of there's. They have beautiful pottery that they put soy sauce in. They have gluten free options on many things on their menu.

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Lua Brewing

1525 High St, Des Moines, IA 50309, USA
Gluten Free IconAccommodating Gluten-Free
Dairy Free OptionsDinnerOpen Late NightOutdoor SeatingVegan OptionsVegetarian OptionsCiderFriesDeliveryTake AwayKid FriendlyPet Friendly
Enjoy a vibrant menu with rotating themes, mouthwatering dishes, and unique drinks that cater to everyone, making it a local favorite.

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Rachel Quist
Rachel Quist
The staff accommodated a large group immediately and we had great service from Annie! They have a whole vegan and gluten free menu if you ask for it. The tofu bites are great! Portions are very generous. A great option in the Des Moines area!

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A Dong Restaurant

1511 High St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerVeganOpen LateDeliveryTake AwayKid FriendlyVegetarian

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MrBubbles4U
MrBubbles4U
I love to eat A Dong! Wife has celiac and can't eat wheat, but they have delicious stir fry for them and rice wrap spring rolls as well. Very good food over all!

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Zombie Burger + Drink Lab

300 E Grand Ave, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerBrunchOpen LateCocktailsBurgersGrab & GoDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyRestaurant
A fun spot with a vibrant patio, unique milkshakes, and a welcoming vibe that's perfect for a relaxed outing with your furry friend.

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Josh Anderson
Josh Anderson
This place was awesome, staff was friendly and helpful, did not feel rushed. Staff helped us figure out how to make items Gluten-free for my Fiancé. Some shakes are also Gluten-free l. Just like all restaurants there is a chance for cross contamination but let staff know and they can help the best they can.

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El Patron Authentic Mexican Cuisine

4351 Merle Hay Rd, Des Moines, IA 50310, USA
Gluten-free options
LunchDinnerOpen LateMexicanDeliveryTake AwayOutdoor SeatingKid FriendlyBar
Amazing spot for road trippers, known for the best fajita veggies around—definitely a must-visit in your travels!

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Arrow Austin
Arrow Austin
I'm on a road trip with my dad and we decided to stop for some food. It was delicious, very well may be the best fajita veggies I've had ever. I'll definitely come back on my next road trip. I'm not kidding when I say they were AMAZING! They were also good with my allergies, I have celiac disease and am allergic to dairy. It's been a few hours and I have no symptoms of cross contamination!

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Drake Diner

1111 25th St, Des Moines, IA 50311, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LateAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant

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Jody Griggs
Jody Griggs
Not a dedicated gluten-free kitchen but the server made sure my breakfast had no toast with my gluten-free omelet. Tasty.

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The Stuffed Olive Des Moines

216 Court Ave Suite 100, Des Moines, IA 50309, USA
Gluten-free options
DinnerBrunchOpen LateDeliveryTake Away

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M W D S
M W D S
We found out by accident that our waitress was new but you would never know it. She was attentive and was able to answer our in-depth questions. I am a Celiac and needed gluten free, and she made sure to find out that it was an allergy and not a preference. The food was delicious! We will definitely go again next time we are in Des Moines.

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Dunkin'

3611 SE 14th St, Des Moines, IA 50320, USA
Gluten-free options
BreakfastLunchDinnerBrunchBakeryOpen LateCafeGrab & GoDeliveryTake AwayKid FriendlyBread Items

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Libby Banagale
Libby Banagale
I was there just to have a place to wait for a ride home after my car was towed to a garage. I don't eat gluten, so no donuts for me. I ordered a coffee and fried potatoes. The potatoes were not very good, but the coffee was. I was there for over 3 hrs. I drank a lot of coffee and chai. The girls behind the counter were so gracious and concerned. I received service beyond expectations and in a very clean dining area an bathroom. The donuts and menu did look very, very, very good!

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Johnny's Italian Steakhouse

6800 Fleur Dr, Des Moines, IA 50321, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LateItalianDeliveryTake AwayKid FriendlyBar

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Jason Reis
Jason Reis
On a Monday night our waitress was great. Was dining with friend with celiac disease and they were amazingly accommodating. The mushrooms were excellent. And the drinks were strong but not over the top.

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Vibes Kitchen & Bar

1303 Walnut St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerOpen LateDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyRestaurant
Dive into a vibrant drink selection with a fantastic cocktail variety; perfect for a fun night out without breaking the bank.

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Isaac Slings
Isaac Slings
A wide arrange of drinks! Great variety of food. Didn't get a refill on our waters but had a nice array of 8 cocktails. $100 bill for two with 4 cocktails wasn't a bad time. The mojito options are plentiful. Gluten free buns are also available

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Applebee's Grill + Bar

3900 Merle Hay Rd, Des Moines, IA 50310, USA
Gluten-free options
BreakfastLunchDinnerOpen LateAmericanDeliveryTake AwayKid FriendlyRestaurant

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Alicia Andrews
Alicia Andrews
Always willing to listen for special orders, i.e. gluten free. Just need ask. Bartender is great and good conversation!-if you want to chat. Food hot and delicious. Combos husband and I can share with G.F restrictions.

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Big Grove Brewery & Taproom

555 17th St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerOpen LateDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyBarRestaurant
This spot impresses with its stunning design featuring an airy vibe and industrial elements, plus it’s a cozy go-to with great seating options.

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Melinda Bianchi
Melinda Bianchi
The first thing you'll notice about this place is how beautiful it is. The design is flawless, melding an open-air, wispy feel with clean, industrial look. Whoever designed this place is brilliant! I've been here 3x since they opened over the summer. The first week they were open it was pretty crazy but somehow they got hot, delicious food out quickly. Drink service took a little longer but it wasn't horrible. Great teamwork! Now that the hype has died down a little bit and it's winter, I can judge it a little better. The food here is still amazing! Still delicious, still hot, still comes out quickly. I've gotten a different entree every time I've visited and have never been disappointed. My friends who are vegan and gluten-free also love the menu here! Drinks come a lot quicker now that there aren't 1000 people swarming the place. The beer is tasty, obviously. Their cocktail specials are also really good! They have tons of tables inside for dining. Lots of seats around the bar. We brought our dogs with us over the summer and sat on the patio. The wait staff was always gracious enough to bring our pups water. I don't usually visit a restaurant more than once but this is a recurring go-to in Des Moines. Highly recommend!

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Smokey Row Coffee

1910 Cottage Grove Ave, Des Moines, IA 50314, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LateCafeDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly

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Bill Davis
Bill Davis
Great place with good beverages & food. Try the Sweet Georgia Brown iced or hot (I wish they did it Ice-blended too.) or the Café Borgia! Try the breakfast casserole or the taco salad! Good bakery treats too, even a few that are gluten-free (much appreciated). Book a meeting room or gather with friends. Can get busy with college students and locals though, so consider booking a room to ensure space for more than a few people.

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Northern Lights Pizza

4211 SW 9th St, Des Moines, IA 50315, USA
Gluten-free options
LunchDinnerOpen LateItalianPizzaDeliveryTake AwayKid Friendly

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nicole ponce
nicole ponce
Amazing pizza! My family raves about this place so I thought I’d give it a try while I was in town visiting. They had gluten free options which was a plus! And they use Graziano sausage! Yummy!

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Big Tomato Pizza

2613 Ingersoll Ave, Des Moines, IA 50312, USA
Gluten-free options
LunchDinnerOpen LatePizzaDeliveryTake AwayPet Friendly
Known for amazing flavors, this spot serves pizza that leaves you craving more and happy instead of feeling sluggish afterward.

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Jaime Kallai
Jaime Kallai
We've now ordered for delivery 3 times from Big Tomato and HANDS DOWN THE BEST PIZZA I've ever had! I always get stomach aches after eating pizza, but NOT with Big Tomato's pizza and I'm SO happy to find this out because I LOVE PIZZA! My favorite is their gluten free tomato, basil, and mazzerella cheese!!!! It's to die for!! I have had 4-5 flavors and there all amazing!!!

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