Top 18 Gluten-Free Sandwich Spots Across Greenville

Your curated guide to gluten-free dining options, with detailed reviews and recommendations for safe celiac-friendly meals.

Grill Marks - Main St. Greenville

209 S Main St, Greenville, SC 29601, USA
Gluten Free IconCeliac friendly
BurgersDinnerPet FriendlyKid FriendlyLunchOutdoor SeatingTake AwayGF MenuDedicated GF FryerFriesKnowledgeable StaffBread ItemsDessertsSandwichesBrunchDelivery
This spot offers a fun atmosphere, great options for everyone, and juicy burgers with a fantastic outdoor dining experience.

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Tracy Johnson
Tracy Johnson
As someone with Celiac Disease, eating out is VERY limited! I am grateful for Grill Marks. Been to Greenville and Columbia multiple times over the past decade. I have never had an issue with gluten cross-contamination here! I appreciate the fries, etc are also dedicated gluten free. My burger is always cooked as ordered. For the price, the value of food quality and service level are completely on par. I will continue to return and if I have a singular experience below the norm, I will still give them another shot!

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Dedicated gluten-free menu

Nose Dive

116 S Main St, Greenville, SC 29601, USA
Gluten Free IconCeliac friendly
BrunchAllergen FriendlyBreakfastDinnerKid FriendlyLunchOutdoor SeatingTake AwaySandwichesCocktailsBread ItemsDedicated GF FryerBeerBurgersDessertsFish & ChipsFriesOpen LateDelivery
A vibrant spot in downtown Greenville, known for its delicious offerings and inviting atmosphere, making it a must-visit for locals and travelers alike.

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Hailey
Hailey
Great place for gluten free options, I had the mac and cheese. Drinks were good too!

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Gluten-free options are marked

Sully’s Bagel & Deli

6 E Washington St, Greenville, SC 29601, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchOpen LateSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items
With a vibrant courtyard and bustling atmosphere, this downtown spot elevates the breakfast sandwich experience, making it a favorite for locals and visitors alike.

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Hailey
Hailey
Had there gluten free bagel and it was the best I have ever had!

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Schlotzsky's

103 Old Boiling Springs Rd, Greenville, SC 29615, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread ItemsBreakfast
A cozy deli known for its impressive variety and standout flavors that keep fans coming back for more.

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Danielle Bradley-Allen
Danielle Bradley-Allen
I'm so glad they offer gluten free bread now so I can go back to eating here more often. Has always been one of my favorites.

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Local Cue Sports Bar

30 Orchard Park Dr Suite 7, Greenville, SC 29615, USA
Gluten Free IconCeliac friendly
GrillDairy Free OptionsDinnerOpen Late NightLunchTake AwayDedicated GF FryerBread ItemsSandwichesAmericanBreakfastBrunchDeliveryKid FriendlyRestaurant
A lively spot with a fun atmosphere and a diverse menu that caters to various dietary preferences, perfect for a casual hangout.

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Caitlin V
Caitlin V
My husband and I had lunch here for the first time today and definitely will be back. Our server was phenomenal, I wish we got her name (long redish hair with bangs and glasses) she happily answered our 100s of questions. I'm, unfortunately, gluten free and I love that there's a separate menu with more than "burger no bun". I came in to try the gf mac and cheese topped with brisket and it was out of this world. Whatever pasta they use is the best gf pasta I've had, it doesn't fall apart like other gf pastas. The portion was huge and I have more than half for lunch tomorrow. My husband got the cheesesteak, he said it was great and LOVED the bbq rub fries.

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Dedicated gluten-free menu

Jersey Mike's Subs

1511 Woodruff Rd, Greenville, SC 29607, USA
Gluten Free IconAccommodating Gluten-Free
LunchAllergen FriendlyBreakfastBrunchDairy Free OptionsDeliveryGrab & GoKid FriendlyOutdoor SeatingTake AwayVegetarian OptionsVegan OptionsBread ItemsSandwichesDinnerPet Friendly
With a quirky submarine shop vibe, this spot will satisfy your cravings with heavenly bread, meat, and toppings, all at wallet-friendly prices!

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Don Chapman
Don Chapman
I just had a gluten-free cheese steak sub from the night crew on the weekend and it was the best sub I have ever had from a Jersey Mike's!

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Gluten-free options are marked

Chicken Salad Chick

3604 Pelham Rd, Greenville, SC 29615, USA
Gluten-free options
LunchDinnerCafeSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items

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Dana B.
Dana B.
My new go-to dessert... the Grape Salad! Only 138 calories, gluten- free and vegan, " red and white seedless grapes covered in a sweet cream cheese mixture, topped with brown sugar and crushed pecans." If you like grapes, give this a try! And, after a great lunch, stop by Emily Austin - right next door!

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Jersey Mike's Subs

3280F N Pleasantburg Dr, Greenville, SC 29609, USA
Gluten-free options
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyBread Items

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free_people_ smile
free_people_ smile
Delicious gluten-free bread and cookies!

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Jersey Mike's Subs

215 Pelham Rd B 206, Greenville, SC 29615, USA
Gluten Free IconAccommodating Gluten-Free
LunchGrab & GoKid FriendlyTake AwayVegetarian OptionsVegan OptionsBread ItemsSandwichesDinnerDeliveryPet Friendly
Known for excellent sandwiches and a welcoming vibe, this spot is super accommodating and perfect for anyone with dietary preferences.

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Ryan Thackray
Ryan Thackray
Staff here are great and sandwiches are excellent. Very allergen friendly. I have celiac disease and need to avoid gluten. They have gluten free rolls and are trained to wipe down equipment and avoid any cross contamination. And they were happy to do so! Thanks Jersey Mikes!

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McAlister's Deli

1726 Augusta St, Greenville, SC 29605, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerSandwichesDeliveryTake AwayKid FriendlyBread Items

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Benson Quattlebaum
Benson Quattlebaum
The food is really good. The price is a little steep for sandwiches. They did just start offering gluten free bread.

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Jersey Mike's Subs

1818 Augusta St Ste 110, Greenville, SC 29605, USA
Gluten-free options
LunchDinnerSandwichesDeliveryTake AwayPet FriendlyKid FriendlyBread Items

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Roberta Hames
Roberta Hames
Great employees. I didn't care to much for the taste of the gluten free bread. But besides that the rest of the sandwich was fresh and delicious. Will try lettuce wrap instead of toasted gf bun

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Subway

1602 Laurens Rd, Greenville, SC 29607, USA
Gluten-free options
BreakfastLunchDinnerSandwichesDeliveryTake AwayKid FriendlyBread Items

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S. E. S. Cuellar
S. E. S. Cuellar
Great sandwiches if you know how to place an order. ;) I haven't been recently, but a selection of gluten-free breads would be much appreciated!

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Chicken Salad Chick

15 Garlington Rd, Greenville, SC 29607, USA
Gluten-free options
LunchDinnerCafeSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items

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Marissa DeRemer
Marissa DeRemer
Chic boutique atmosphere. Amazing customer service. They will even let you sample the salads. Good value. Plenty of gluten free options. Can't wait to return.

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Atlanta Bread Cherrydale

3203 N Pleasantburg Dr, Greenville, SC 29609, USA
Gluten-free options
BreakfastLunchDinnerBrunchBakeryCafeSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread ItemsRestaurant

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Pearl Rubin
Pearl Rubin
Gluten free bread replacement options!! Great atmosphere, friendly staff! Will definitely be back!

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Jimmy John's

141 E McBee Ave., Greenville, SC 29601, USA
Gluten-free options
LunchDinnerSandwichesGrab & GoDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items

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Dane Wilson
Dane Wilson
My wife has Celiac Disease, so gluten free is a requirement. The guys helped understand what her options were. Great service, a really affordable option for quick and affordable downtown.

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Clayton's Deli

1628 E North St #2, Greenville, SC 29607, USA
Gluten-free options
BreakfastLunchDinnerSandwichesDeliveryTake AwayKid FriendlyBread Items
Experience a vibrant atmosphere and deliciously unique dishes at this hidden gem that's quickly becoming a local favorite!

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Corey Spearman
Corey Spearman
So fortunate to have been told about the best new lunch spot in Greenville! The service and atmosphere were incredible! The best BLT I've ever had to be honest! The whole fried okra was delicious and only $3! Definitely check them out! 10 out of 10 will definitely recommend! Also, The Pound Cake Man has cupcakes and cake available with gluten free options as well!

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