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New Yorkers 1st Choice
Uptown, Chicago's best

American sandwich spots

Made for those who appreciate the straightforward reliability of a classic American sandwich.

Based on 715 Opinions
+712
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Updated April 2026
01
Uptown Deli image 1
Uptown Deli image 2
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Corner store with friendly neighborhood vibe offers massive, affordable sandwiches and an interesting assortment of local products. Atmosphere stays welcoming and lively, with free dog treats adding to the community feel.

Stacked with a large amount of meat, the Reuben sandwich fills you up for the day. Subs, paninis, Italian beefs, and nachos also deliver solid American deli flavors.

Beef sandwiches stand out with Italian beef that wins contests. Breakfast and lunch sandwiches are addictive, and the veggie sandwich is noteworthy.

People are saying

"I thought their sandwiches were amazing and a great buy."

"The staff at this convenience store is always friendly and helpful."

"The American Food here is served by super friendly staff."

Good to know

1

Uptown Deli is open until midnight for food and 24-hour grocery shopping.

2

They offer gluten-free bread and a variety of snacks and fresh produce.

3

Expect some prices for snacks and juices to be higher than average.

02
Ragadan image 1
Falafel restaurant

Small, clean space with live plants and aesthetic decor creates a cozy, casual atmosphere. The vibe is inviting and comfortable, suited for quick, quality meals. Known for top-notch burgers and crunchy falafels, it offers excellent value and fresh ingredients.

Bold, flavorful patty melts stand out with beef patties, bacon, caramelized onions, pickled jalapenos, and a special mayo-mustard on sesame ka'ak bread. The double cheeseburger also delivers a rich, comforting taste.

Falafel sandwiches stand out with bold flavors and fresh sauces. Chicken and lamb options come breaded and flavorful, while the eggplant sandwich offers a unique twist. Prices stay reasonable with combos under $40.

People are saying

"The Oklahoma onion burger is amazing and exceeded expectations."

"I found the falafel and chicken sandwiches delicious and savory."

"This American Food patty melt was one of the best I've ever eaten."

Good to know

1

Reservations are not required but seating is limited.

2

Prices range from $7 to $11 for high-quality burgers.

3

Credit cards and mobile payments are accepted; cash is also welcome.

03
NORTH BUENA DELI (UPTOWN) image 1

Sandwich shop with welcoming interior and outdoor seating offers a neighborhood staple vibe filled with house music. It draws a busy crowd enjoying handmade sandwiches and a unique liquor selection. Noise level can be high, creating an energetic atmosphere.

Buffalo club sandwich stands out as a key American dish here. Chocolate chip cookies and Kleins brownies from a nearby Venezuelan bakery add sweet options.

Fresh deli sandwiches use great quality meat and come with a packed selection of wines. The chicken chipotle and turkey reuben with giardiniera stand out as flavorful options.

People are saying

"I thought the sandwiches here were the best and so yummy."

"They have a great selection of cold beer and wine."

"I thought the American Food, especially the sandwiches and cookies, was delicious and affordable."

Good to know

1

Expect long wait times during peak hours, especially on weekends.

2

Parking can be challenging, particularly during busy lunch hours.

3

Credit cards and mobile payments are accepted; cash is also welcome.

04
BoJono's Express image 1
Pizza restaurant

Quaint shop with new decor and a small menu offers a cozy vibe suited for quick, affordable meals. The space has limited seating, making it better for takeout than dining in. The atmosphere feels reimagined and welcoming for lunch and early dinner.

Pot roast sandwich stands out with its tender, flavorful meat packed generously. Chicken wings, meatball sub, and chicken noodle soup also deliver solid, classic American flavors.

Chicken parmesan sandwich stands out with rich flavor and tender meat. Pot roast sandwich packs more pot roast than usual and tastes better than grandma's. Eggplant parm and meatball sandwiches also deliver solid, delicious options.

People are saying

"This American food's pot roast sandwich is tender and packed with flavor."

"I found the chopped chicken salad fresh and tasty."

"The pot roast sandwich tasted like a decades old family recipe."

Good to know

1

BoJono's Express reopened in November and serves lunch and early dinner.

2

The restaurant offers a great selection of sandwiches, salads, and daily specials.

3

Prices are very affordable, with meals typically around $15.

05
Cuckoo image 1
Restaurant

Small, cozy restaurant with a bright yellow interior and plushie chicken decorations creates a cute, welcoming vibe. The atmosphere stays quiet and relaxed, suitable for dine-in or takeout. Seating is ample despite the compact space, supporting a casual, friendly experience.

Fried chicken here is super crispy and juicy with multiple amazing fried chicken sandwiches. The wings come in flavorful options like coconut curry and plain, making it a go-to spot for fried chicken lovers.

Multiple fried chicken sandwiches stand out for their crispy texture and juicy flavor. Varieties like the garlic soy and honey mustard offer distinct, satisfying tastes with perfect marination.

People are saying

"The chicken sandwich here is super crispy and juicy."

"I found the chicken sandwich to be extremely crispy and satisfying."

"The American Food here, especially the fried chicken, is super crispy and juicy."

Good to know

1

Reservations are not required, but calling ahead for takeout is recommended.

2

Expect a 10-15 minute wait for food preparation during busy hours.

3

The average cost for two people is around $30.

06
Tiffany's On Broadway image 1

Small space offers a cozy, laid-back atmosphere with comfortable decor and a unique, chill vibe. Loud club music and cartoons play, creating a lively yet casual setting. BYOB policy with a nearby liquor store adds to the relaxed, local feel.

Steak and Eggs features juicy steak cooked medium rare with two tasty salsas. The Mac and cheese is fresh and sassy, and the club sandwich stands out as very flavorful. Both the Triple B Burger and calamari are also delicious.

Club sandwich stands out with its juicy, flavorful layers and a buttery, toasty bun. Carnitas and chimichurri chicken sandwiches offer rich, bold flavors, often paired with shoestring or steak fries.

People are saying

"The Steak And Eggs here are delicious and perfectly cooked."

"The American Food here, especially the steak and eggs, is juicy and cooked perfectly."

"This club sandwich is juicy and flavorful, the best I've had."

Good to know

1

Tiffany's On Broadway is BYOB, and there is a liquor store next door.

2

Expect longer wait times if the kitchen is busy due to limited staff.

3

The food comes out as it is ready, not all at once.

07
EL RINCON DE FABIO LLC image 1
Venezuelan restaurant

Small space filled with beautiful Venezuelan decor and a cozy, family-friendly atmosphere. Latin music plays softly, creating an awesome vibe that feels welcoming and pleasant. Outdoor patio offers a nice option for seating in good weather.

Fried chicken stands out with its crispy texture and rich flavor. Sauces add a crazy delicious kick, and sides like fries and veguera arepa complement the meal well.

Plantain and patacones sandwiches stand out with rich flavors, especially the brisket and pork varieties. The Queen Sandwich features chicken and adds variety to the menu.

People are saying

"I found the pabellรณn arepa to be delicious."

"The fried chicken here is delicious, truly good to the bone."

"The plantain sandwich here is phenomenal and delicious."

Good to know

1

Free drinks are offered after 5pm every day.

2

Enjoy free margaritas daily after 2:00 PM.

3

Free wine is available on Fridays.

08
Lucy's Fried Chicken & Smashburgers image 1

Retro decor with 60s and 70s vibe creates a homey atmosphere filled with loud, energetic music. Tables wobble on tiled floors, and self-serve condiment stations add a casual touch. The place draws people looking for noteworthy fried chicken and smashburgers with flavorful sauces.

Fried chicken stands out with its tender, well-seasoned quality and includes a notable bacon jam fried chicken sandwich. The menu stays simple, focusing on classic diner-style American food like smashburgers and mac and cheese.

Huge pieces of chicken with extra crispy batter define the sandwiches here. The bacon jam fried chicken sandwich and the spicy classic chicken sandwich stand out for their juicy, flavorful profiles.

People are saying

"I found their chicken sandwich to be one of the best I had."

"The spicy chicken sandwich was perfectly fried and flavorful."

"The American Food burgers here are amazing, especially the bacon jam cheeseburger."

Good to know

1

The restaurant offers buy-one-get-one-free fries, shakes, and Mac at certain times.

2

Sandwiches do not come with fries, which is an additional cost.

3

The meal cost around $30 for a burger, fries, and a drink.

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