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The 9 Best Gluten-Free Cocktail Spots in Des Moines

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By Gluten Free Eats' gluten-free community

Updated Jul 2025

01
Bar Nico

Bar Nico

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100% Dedicated Gluten-Free

428 E Locust St, Des Moines, IA 50309, USA

GF OptionsMexicanCocktailsAllergen FriendlyDinnerOpen Late NightLunchTake AwayVegetarian OptionsVegan OptionsTacos100% GFCeliac FriendlySeparate GF MenuSeparate OvenKnowledgeable StaffDedicated GF Kitchen SpaceDessertsDedicated GF FryerBreakfastBrunchDeliveryPet FriendlyKid FriendlyOutdoor Seating
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Jacinda Daniel

Everything is gluten free which was amazing, I didn't have to worry about only getting to choose from two items on the menu. The salsa options were a bit odd, there was a cheese/yogurt type dip among the four they give you and it just didn't fit with the Latino flavors well, it was more Mediterranean in taste. Definitely pricier for how much food you get but the chips are a free refill. When I asked about diet pop options I was told they didn't have any but they have what appeared to be a full bar with a fountain pop sprayer (which normally would have at least one diet option). The only thing I could have to drink was water there (I'm a type one diabetic and regular pop is a bad situation).

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Dedicated gluten-free menu
02
Louie's Wine Dive

Louie's Wine Dive

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Celiac friendly

4040 University Ave suite a, Des Moines, IA 50311, USA

Wine BarCocktailsAmericanBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingSeafoodTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBeerCeliac FriendlyOpen LateDeliveryPet FriendlyRestaurant
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Stephanie Dowdy

Love this place. Great gluten free options & excellent service!

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03
Americana

Americana

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Celiac friendly

1312 Locust St, Des Moines, IA 50309, USA

AmericanBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerCiderDessertsCeliac FriendlyKnowledgeable StaffKid FriendlyPancakesBread ItemsSandwichesCocktails
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Endless food and bottomless mimosas/bloody marys/mixed drinks is a hell of a way to start a weekend. Staff is very friendly and attentive. Food is delicious and there were plenty of options for gluten free eaters.

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04
Fresko

Fresko

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Celiac friendly

909 Locust St Ste. 103, Des Moines, IA 50309, USA

CocktailsBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerKid FriendlyOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBread ItemsBurgersDessertsSandwichesTacosCeliac FriendlyRestaurant
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Mijo Martinez (Mijo Martinez)

My chicken chiabatta sandwich was a bit dry and the food selection was limited, but they did have substantial gluten free options. The setting and staff were very nice, making it an overall excellent experience.

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05
St. Kilda Cafe & Bakery

St. Kilda Cafe & Bakery

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Gluten-free options

300 SW 5th St, Des Moines, IA 50309, USA

BreakfastLunchDinnerBrunchBakeryOpen LateCafeCocktailsDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
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Brooke Weber

I have been here several times recently for brunch. This place knows what they are doing and they are really good at it: the atmosphere, the decor, the food, the service. The lattes here are the best in the area, hands down. Even the cups and saucers are beautiful and add to my enjoyment of the coffee drinks. I want the exact cups for my own home. The seasonal latte flavors are creative and never overly sweet. I do love a pumpkin spice latte, and St. Kilda has the best. I was interested in a seasonal mocha and was hesitant to order it for fear it would be too sweet, but the server told me more about it so I decided to try it. It was the best mocha I’ve ever had with the perfect balance of flavors and just the right amount of sweetness. Everything that’s a part of the Big Aussie Breakfast is prepared to perfection: thick cut bacon, delicious blistered roasted tomatoes, perfectly crispy house-made bread. Even the gluten-free bread is excellent. Last week my boyfriend got a hashbrown on the side and it was the best hashbrown I’ve ever had - a lovely soft texture on the inside and perfectly crispy all the way around on the outside. The last 3 times I’ve eaten there, we’ve had the same server. I love her! Very friendly, relatable, and a bit quirky in the best possible way. After our last visit, I decided St. Kilda in Valley Junction is my favorite place for brunch.

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