Top 38 Gluten-Free Dinner Spots to Delight in Midtown - Downtown, Columbia

711 Gervais St, Columbia, SC 29201, USA
Gluten Free IconCeliac friendly
GrillBurgersCocktailsAmericanAllergen FriendlyDairy Free OptionsDeliveryDinner
This spacious spot offers a pet-friendly porch and a lively bar with numerous TVs, creating a vibrant atmosphere. It stands out as a gluten-free haven with a dedicated fryer and a wide variety of tasty gluten-free options, ensuring a safe and enjoyable dining experience.

People are saying
View more
Terrie Potts
Terrie Potts
Great gluten free options.

Menu
View menu
Gluten-free options are marked

1009 Gervais St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
PizzaVegan OptionsDairy Free OptionsDeliveryKid FriendlyLunchTake AwayVegetarian Options
Set in a cool old apothecary building, this spot offers a fun, lively atmosphere with quirky decor and vintage tracks. The upstairs seating provides a cozy vibe enhanced by tasteful wall art and good music, making it a chill environment ideal for those seeking gluten-free options in a welcoming setting.

People are saying
View more
Stephanie Greer
Stephanie Greer
They took our group of 20 elementary school kids and 6 adults without a reservation. The food came incredibly fast, tasted good and the waitress was amazing. She worked around the kids, gluten intolerance, and food allergies like a pro

Menu
View menu

1301 Main St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
MexicanCocktailsDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingVegan Options
This lively spot offers a fun and energetic atmosphere with plenty of bar seating and TVs for sports fans, plus an inviting outdoor space. It stands out for its clearly marked gluten-free options and attentive service, making it a stress-free choice for gluten-free diners.

People are saying
View more
sarah rikert
sarah rikert
Cantina is always my go to restaurant especially in the city! The roasted chicken tacos are always my favorite! They have so many gluten free options too! The service at the bar or if you are sitting at a table is always amazing! The manager was very informative on higher shelf tequila and helped our group out tremendously! I will always recommended cantina! Can’t wait to visit again!

Menu
View menu
Gluten-free options are marked

804 Gervais St Suite 100, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateAmericanPizzaDeliveryTake AwayPet Friendly
This lively spot offers a laid-back, family-friendly atmosphere with a gluten-free menu that includes standout pizza options. The friendly service and gluten-friendly environment make it a top choice for those seeking quality gluten-free dining in a vibrant setting.

People are saying
View more
MMS Howell
MMS Howell
Food was hot and fresh; a little peppery. My burger was supposed to be lettuce wrapped since they were out of the gluten free wrap. Nice atmosphere.

Menu
View menu
Gluten-free options are marked

918 Gervais St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchDeliveryTake AwayOutdoor Seating
Set in a charming old building with high ceilings and exposed brick, this bistro offers a peaceful, elegant atmosphere with cozy tables and a hip vibe. The friendly, knowledgeable service ensures a welcoming experience for gluten-free diners.

People are saying
View more
Steven Hammond
Steven Hammond
Incredible food drinks and desert. I had a carrot cocktail which was amazing, yummy quail and local cheese, amazing SC fresh shrimp and the best grits I have ever had in a restaurant. To top it off a delicious gluten free and dairy free desert cake that was remarkable and one of the best gluten free desserts I have ever had. Service was perfect and great knowledge of all the foods and dietary restrictions. One of the best restaurants I have been to all year.

Menu
View menu

1425 Sumter St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerBrunchDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
This eatery offers a laid-back, artsy vibe with a cozy Southern charm, creating a welcoming retreat. Known for being gluten-friendly, it accommodates dietary needs with care, making it a great spot for those seeking a gluten-free dining experience in a creative, relaxed setting.

People are saying
View more
Meg Cook
Meg Cook
Great vibe. Accommodated allergies (gluten free) and my kids enjoyed it. Especially liked the fancy grilled cheese.

Menu
View menu

1102 Huger St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerGrab & GoDeliveryTake AwayPet FriendlyKid FriendlyAsian
Step inside a stylish, spacious interior that feels bright and inviting, offering loads of seating for a relaxed dining experience. The clean, friendly atmosphere complements the many gluten-free protein and base options, with gluten-free sauces like sriracha and soy enhancing the fresh, high-quality offerings.

People are saying
View more
Susan Weakley
Susan Weakley
Great fresh food! There are ample gluten free protein choices and base choices. The sauces for GF are either sriracha or GF soy sauce or wasabi which is good, but I would so love to see a ginger soy sauce gf option. Still it is clean, bright, friendly and tasty.

Menu
View menu

700 Harden St, Columbia, SC 29205, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateDeliveryTake AwayOutdoor SeatingKid FriendlyBar
This lively spot offers a vibrant college town bar atmosphere with 7 TVs showcasing Gamecock sports and a soundtrack of great music that energizes the space. The staff is attentive to gluten and onion allergies, ensuring a safe and welcoming environment for gluten-free diners.

People are saying
View more
Brian P.
Brian P.
Very tasty BBQ in vibrant Five Points Columbia! Nice selection of sides. Some meats and sides were out during our visit. Good drinks and wonderful service. Took our gluten and onion allergies seriously. Loved having a huge selection of sauces right on the table. Free onsite parking. Lots of food and shopping nearby. Safe area with lots of activity.

Menu
View menu

823a Lady St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerMexicanCocktailsDeliveryTake AwayOutdoor SeatingBar
This spot offers a vibrant, cozy atmosphere enhanced by soft lighting and tea light candles, creating a welcoming setting for those seeking gluten-free options. Attentive service ensures guests with gluten allergies feel cared for and accommodated throughout their visit.

People are saying
View more
Makaille Granato
Makaille Granato
I have been to Coa twice now with my friends and Dan is a wonderful server. He always makes sure we are taken care of, that we are having a great time, and that everything comes out perfect! My friend has a gluten allergy and he always make sure that anything she orders is gluten free without us even asking! He is a wonderful guy all around and if you go to Coa, Dan is the Man!! Other than the excellent service, I am never disappointed by the amazing food they always have. I love their rice, dobladitas, and my partner fell in love with their off the menu Birria tacos. The drinks are also super well made and they pack a punch so watch out! All in all, Coa is a must if you live or are visiting the Columbia area.

Menu
View menu
Gluten-free options are not marked

2123B Greene St, Columbia, SC 29205, USA
Gluten-free options
LunchDinnerPizzaDeliveryTake AwayOutdoor SeatingKid FriendlyPet Friendly
Chill spot with gluten-free cauliflower crust pizza and a lively patio ambiance with great music.

People are saying
View more
Brian P.
Brian P.
Gluten free crust is an option. Don't forget to try the Blue Italian Doughnuts!

Menu
View menu

1221 Main St #150, Columbia, SC 29201, USA
Gluten Free IconCeliac friendly
LunchDinnerBrunchDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
This elegant venue offers a demure environment with versatile seating options including bar, table tops, and outdoor tented areas. The chill vibe created by a small band complements the gluten-free friendly and knowledgeable service, ensuring a refined and safe dining experience.

People are saying
View more
Robert Heffner
Robert Heffner
Very elegant dining experience! Food is expensive, but worth the splurge for special moments or if you can afford it. Steaks are top notch and premium sides are worth it. Very Gluten Free friendly! Will go again! p.s. might want to call first and make reservations, very popular...

Menu
View menu

922 Main St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerMediterraneanDeliveryTake AwayOutdoor SeatingKid FriendlyPet Friendly
This cozy spot features a 50s-style decor that creates a welcoming atmosphere. The staff is knowledgeable about gluten-free options, ensuring a safe and satisfying experience. The friendly service and clearly marked menu make it an excellent choice for gluten-free diners.

People are saying
View more
LaSandra Teixeira
LaSandra Teixeira
Green Olive is a gem near USC! The food is incredibly tasty, delicious, and fresh. We tried both the chicken and lamb shawarma platters, and they were fantastic. The salads were crisp and flavorful, complementing the meats perfectly. Plus, everything is very affordable, making it a great spot for a quick, satisfying Mediterranean meal. They have pizza so I’ll be back! They also have gluten free and vegan options.

Menu
View menu

1200 Lincoln St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
Set in a beautiful restaurant setting, this place features an elegantly decorated private dining room ideal for celebrations. The friendly and accommodating service ensures guests with gluten sensitivities feel comfortable, with plenty of gluten-free options available.

People are saying
View more
Jeni Floyd
Jeni Floyd
Super super popular, reservations recommended! We had a large party and we were able to get outside seating with a short wait. Inside would have been a lot longer. The only reason I gave 4 stars was one of our party had to send back a steak for being overdone. We had to wait a bit for our food, but it was reasonable considering how slammed the kitchen must have been. Very friendly and accommodating service. We had a party member who has a very restrictive diet, and they were able to serve him easily. Plenty of gluten-free options!

Menu
View menu

1215 Assembly St, Columbia, SC 29201, USA
Gluten-free options
DinnerOpen LateAmericanDeliveryTake Away
Set in a quaint, well-appointed space, this restaurant offers a relaxed, stylish atmosphere ideal for enjoying gluten-free options with confidence. The staff are knowledgeable and attentive, ensuring a safe and pleasant dining experience for those with gluten sensitivities.

People are saying
View more
Amanda “Amyanda76” Hydrick
Amanda “Amyanda76” Hydrick
This is my favorite restaurant in Columbia. They have gluten free options and southern options too good to pass up! And the martinis 🍸❤️

Menu
View menu

1216 Washington St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerOpen LatePizzaDeliveryTake AwayPet FriendlyKid Friendly

People are saying
View more
Rhonda Gaunt
Rhonda Gaunt

Menu
View menu

931 Senate St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateGrab & GoDeliveryTake AwayPet FriendlyOutdoor Seating
Casual eatery with gluten-free options and exceptional customer service for allergy needs.

People are saying
View more
Amanda “Amyanda76” Hydrick
Amanda “Amyanda76” Hydrick
I was so happy to hear an employee know about Brad/gluten allergy! We got great service great food and table at lunch!

Menu
View menu

2338 Main St, Columbia, SC 29201, USA
Gluten-free options
BreakfastLunchDinnerVeganCafeDeliveryTake AwayOutdoor Seating
This charming spot offers a warm, inviting atmosphere with a large outdoor patio perfect for enjoying freshly prepared meals. The gluten-free French toast is notably flavorful and moist, making it a standout choice for those seeking delicious gluten-free options in a cozy, open-air setting.

People are saying
View more
Asad
Asad
Wheat and gluten and soy is harmful to the body please do your research, if that matters to you.

Menu
View menu

2011 Devine St, Columbia, SC 29205, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerAsianDeliveryPet FriendlyKid FriendlyRestaurant

People are saying
View more
Rochell Helmuth
Rochell Helmuth

Menu
View menu

506 Gervais St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
This eatery offers a welcoming and upbeat atmosphere with bright, lively decor and a friendly family vibe. The clean, well-maintained space features an excellent display of toppings and gluten-free bun options, ensuring a safe and enjoyable experience for gluten-sensitive guests.

People are saying
View more
Sherdina Logan
Sherdina Logan
Best hotdog in years. I have gluten allergy so to find a gluten free hotdog place is awesome. 😍

Menu
View menu

1332 Assembly St, Columbia, SC 29201, USA
Gluten-free options
DinnerAsianDeliveryTake Away
Step inside to experience a calm and peaceful atmosphere enhanced by warm lighting and sliding doors, evoking a truly authentic Japanese ambiance. This place is known for being celiac friendly and safe, offering a welcoming setting for gluten-free diners seeking authenticity and comfort.

People are saying
View more
Andrew Mylander
Andrew Mylander
Excellent sushi, Hibachi, etc. Celiac friendly and safe.

Menu
View menu

1307 Main St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerDeliveryTake AwayPet FriendlyOutdoor Seating
Cozy Thai spot with gluten-free and vegan dishes, featuring quick, flavorful meals and stylish outdoor seating.

People are saying
View more
Jonathan Alberti
Jonathan Alberti
Is the cheesecake gluten free?

Menu
View menu
Gluten-free options are marked

1128 Devine St, Columbia, SC 29201, USA
Gluten-free options
BreakfastLunchDinnerBrunchItalianDeliveryTake AwayKid Friendly
Step into a warm, inviting atmosphere reminiscent of old-world Italy, with dim lighting and well-appointed tables creating an intimate, upscale setting. The kind and gracious service ensures a welcoming experience, especially for those seeking gluten-free accommodations in a charming Mediterranean-inspired environment.

People are saying
View more
Matthew willis
Matthew willis
This hidden gem of restaurant was one we just happened to stumble across while site seeing on foot downtown. We didn’t make a reservation, however they were kind enough to fit us in. The menu had some interesting items ranging from different countries surrounding the Mediterranean but having the kids with us meant pizza all around. We went with the gluten free crust on both pizzas and we left with our stomachs happy and full. Definitely worth a try if you’re in the area or just so happen to get semi lost and they can squeeze you in. Oh and the staff were kind and gracious.

Menu
View menu

2013 Greene St, Columbia, SC 29205, USA
Gluten-free options
LunchDinnerBrunchOpen LateDeliveryTake AwayOutdoor SeatingRestaurant
This spot offers a chill, inviting atmosphere with lively music and games on each table, creating a fun vibe perfect for socializing. The staff is super friendly and accommodating, ensuring a great experience for those seeking gluten-free options.

People are saying
View more
Tyler Lyerly
Tyler Lyerly
Had several great experiences here. The tacos and margaritas are delicious. Lots of variety to choose from on the menu. Inviting atmosphere, professional service. Lots of gluten-free options, which is very appreciated.

Menu
View menu

807 Gervais St #103, Columbia, SC 29201, USA
Gluten-free options
DinnerBrunchOpen LateSushiDeliveryTake AwayKid Friendly
This intimate spot features lush foliage at the entrance and walls adorned with local art, creating a nostalgic, laid-back vibe perfect for a relaxed dining experience. The gluten-free menu is thoughtfully offered, making it a welcoming choice for those seeking gluten-free options.

People are saying
View more
Augusta Marshall
Augusta Marshall
A tasty diversion! I appreciated the gluten free menu

Menu
View menu

831 Gervais St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerMediterraneanDeliveryTake AwayKid Friendly
This spot offers a warm, loving atmosphere and a clean, inviting space ideal for a quick, healthy lunch. Its gluten-friendly menu and accommodating service make it a standout choice for those seeking gluten-free options without compromising flavor or quality.

People are saying
View more
Trevor Hall
Trevor Hall
Wife and I love CAVA for a quick, healthy lunch. She's gluten sensitive and their menu is very gluten friendly for her to choose options/substitutions to avoid any problems

Menu
View menu

2009 Greene St STE 106, Columbia, SC 29205, USA
Gluten-free options
LunchDinnerDeliveryTake Away

People are saying
View more
Elaine Cash
Elaine Cash

Menu
View menu

1621 Main St, Columbia, SC 29201, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LateAmericanDeliveryTake Away

People are saying
View more
Alysa Lomax
Alysa Lomax

Menu
View menu

2009 Devine St, Columbia, SC 29205, USA
Gluten-free options
LunchDinnerOpen LatePizzaDeliveryBar
College bar with gluten-free pizza options and a lively, dimly lit gameday atmosphere.

People are saying
View more
Geoff H
Geoff H
Great atmosphere to eat pizza and watch a game. Good drink specials and deals on pizza. Gluten free pizza also available.

Menu
View menu

942 Harden St, Columbia, SC 29205, USA
Gluten-free options
LunchDinnerAsianDeliveryTake AwayPet FriendlyKid FriendlyOutdoor Seating
This spot offers a family atmosphere with a great music vibe that enhances the overall experience. The environment is welcoming and clean, with friendly, enthusiastic staff who ensure a smooth, enjoyable visit, making it ideal for those seeking gluten-free dining comfort.

People are saying
View more
Bobbi Jones
Bobbi Jones
The best! Tasty and Gluten Free!!

Menu
View menu

1031 Assembly St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchDeliveryTake AwayOutdoor SeatingKid Friendly

People are saying
View more
Augustus Herrera
Augustus Herrera

Menu
View menu

1211 Lincoln St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerDeliveryTake AwayOutdoor SeatingKid Friendly

People are saying
View more
Mary Prado
Mary Prado

Menu
View menu

2017 Devine St, Columbia, SC 29205, USA
Gluten-free options
DinnerOpen LateAmericanDeliveryTake AwayOutdoor SeatingBar
This venue offers a sophisticated ambiance with a blend of Sinatra and soft jazz, transitioning to contemporary tunes at a comfortable volume that encourages conversation. Its thoughtful atmosphere makes it an excellent choice for those seeking a gluten-free friendly setting.

People are saying
View more
Halina Schafer
Halina Schafer
Went 1st time last night. Love the atmosphere... they were playing Sinatra, soft jazz, etc when we got there. Bumped up to more contemporary, but not too loud, which was great for conversation. We ordered the 1lb mussels w/Thai chili...YUM! And Beef Borganion...good but could've used more wine. Tuesdays are 25% off bottles of wine. Nice surprise. I do wish there was a goat dish on the menu! The duck tacos were fabulous (& Gluten free if matters for you). We will be going back! OP (or Opie?) the owner and Johanna or server were very gracious!

Menu
View menu

930 Senate St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchDeliveryTake AwayKid FriendlyRestaurant
Set within an elegant hotel lobby, this upscale steakhouse offers a cozy ambiance and a welcoming bar area ideal for relaxed conversation. The attentive, knowledgeable service ensures a safe and comfortable dining experience for guests with gluten sensitivities.

People are saying
View more
Lauren King
Lauren King
Brought my dad here for his birthday. Not my normal haunt and we didnt have reservations (eek). The hostess, Anna, was so kind and sat us in the bar area! (Thank you for helping me avoid a crisis Anna!) My dad had the filet and I had the seabass and mushrooms. The food was great! On top of that, our server, James, was knowledgable and welcoming. I have celiac disease and it's really difficult to dine out. Being service industry myself, and having "eating stipulations," I could not be more thankful to be able to eat GREAT FOOD ... ***SAFELY!*** with knowledgeable and empathetic service! 10/10 all the way around. This may be the new birthday spot to treat everyone I love! Thank yall so very much!

Menu
View menu
Dedicated gluten-free menu

2020 Gervais St, Columbia, SC 29204, USA
Gluten-free options
LunchDinnerBrunchVeganOpen LateMediterraneanDeliveryTake Away
This hidden gem offers a spotless, laid-back setting with simple aesthetics, making it a comfortable choice for gluten-free diners. Guests appreciate the variety of gluten-free options and the attentive service, ensuring a welcoming experience for those with dietary needs.

People are saying
View more
Katelyn kelly-morris
Katelyn kelly-morris
Such a great vegan and gluten free options. Love the service and options will keep going.

Menu
View menu

650 Lincoln St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerSandwichesDeliveryTake AwayPet FriendlyKid FriendlyBread Items
This lively spot buzzes with an active, energetic vibe amplified by concert-like music that invites everyone to sing along. The clean, welcoming environment and thoughtful separation of gluten-free utensils ensure a safe and enjoyable experience for gluten-free diners.

People are saying
View more
Richard Godfrey
Richard Godfrey
My wife appreciated the separation of gluten free utensils. Our home store doesn't follow those guidelines. Keep up the great work!

Menu
View menu

601 Main St Suite 100, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerDeliveryKid FriendlyRestaurant
This vibrant spot dazzles with Day of the Dead decor and laser lights, creating a festive yet nightclub vibe. Its artistic touches throughout enhance the atmosphere, making it a lively and welcoming place for those seeking a gluten-free friendly environment with great service and ambiance.

People are saying
View more
Smith Familyof4
Smith Familyof4
We really liked the food, atmosphere and service was pretty good. I am Gluten free and I was very impressed with all the options. We ordered birria tacos- delicious, a burrito but came out as a bowl- steak was fantastic, rice and toppings very flavorful, and the taquitos-these were good, big chucks of chicken inside. These were the bad- the men's restroom was very dark (blue light only) kind of sketchy, the register in the front didn't seem to work so our credit card was gone for a bit trying to run it, our bill (which my husband never checks before paying) was almost $10 more that what we thought. The lunch prices are not what we were charged- ex. side of guacamole was $8 not $4, cheese & street corn were $5 not $4, burrito was $3 more than marked. We would still go back in the future when in town. And we would definitely recommend the house margarita too.

Menu
View menu

1212 Hampton St, Columbia, SC 29218, USA
Gluten-free options
LunchDinnerDeliveryKid FriendlyRestaurant
Quaint spot with top-notch gluten-free menu and warm Venezuelan hospitality.

People are saying
View more
Stan Petit
Stan Petit
The folks inside are so nice, they’ve gone out of their way to provide excellent service over and over. The food is delicious and the best gluten free menu in town.

Menu
View menu

916 Gervais St, Columbia, SC 29201, USA
Gluten-free options
LunchDinnerBrunchOpen LateAsianCocktailsDeliveryPet Friendly
This welcoming spot offers a friendly and caring vibe, creating a comforting atmosphere for those seeking gluten-free options. The inclusive setting and attentive service make it an excellent choice for guests prioritizing gluten-free dining in a warm environment.

People are saying
View more
Courtney Salter
Courtney Salter
Raynaldy and Kelsey at the bar were awesome and so friendly! Made great drinks too. Food and service was great and overall the vibe was friendly and caring. Def recommend. Gluten free options

Menu
View menu

© 2025 Atly - Your Local Guide to Gluten-Free Dining