Top 14 Gluten-Free American Diners to Experience in Des Moines

Your curated guide to gluten-free dining options, with detailed reviews and recommendations for safe celiac-friendly meals.

Louie's Wine Dive

4040 University Ave suite a, Des Moines, IA 50311, USA
Gluten Free IconCeliac friendly
Wine BarCocktailsAmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingSeafoodTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBeerOpen LateDeliveryPet FriendlyRestaurant
A favorite local spot with a vibrant patio and a diverse menu that keeps everyone happy, offering fun shareable bites and tasty drinks.

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Harv
Harv
This place is a gluten-free haven.

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Gluten-free options are marked

Americana

1312 Locust St, Des Moines, IA 50309, USA
Gluten Free IconCeliac friendly
AmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerCiderDessertsKnowledgeable StaffKid FriendlyPancakesBread ItemsSandwichesCocktails
A lively spot with a vast menu and unique stations, perfect for groups but challenging for those with mobility issues due to stair access.

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Jennifer VanSickle
Jennifer VanSickle
Love it every time. Good atmosphere and I'm pretty find if the gluten sensitive choices. Well worth it.

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Buzzard Billy’s

615 3rd St, Des Moines, IA 50309, USA
Gluten Free IconAccommodating Gluten-Free
AmericanDinnerKid FriendlyOpen Late NightLunchTake AwayBread ItemsCiderBreakfastBrunchDeliveryOutdoor SeatingRestaurant
Unexpectedly fun spot with a lively, sports bar vibe, plus a standout cocktail selection and a variety of delicious menu options.

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Cortez Jones
Cortez Jones
Had the BEST experience here. Trying to find a restaurant that offers a gluten free menu as well as regular with no discernible differences in taste is 1 in a million and buzzard Billy’s is exactly that. Any time we ever come back it will be good at BB. Kristen, Kela and shiree are the best servers EVER!

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Dedicated gluten-free menu

Tupelo Honey Southern Kitchen & Bar

665 Grand Ave Ste 100, Des Moines, IA 50309, USA
Gluten-free options
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
Enjoy a cozy vibe with unique patio space for pups while savoring delicious comfort food that feels like home.

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Jennifer Bartlett
Jennifer Bartlett
Shrimp and grits, collard greens with bacon...I felt like I was back home. The gluten free options are limited, but they are done well!

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Bubba

200 10th St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerBrunchAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
Experience a lively vibe with top-notch Southern dishes and mixed drinks, plus a menu that promises something for everyone!

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Ben Miller
Ben Miller
Went in on a quiet Thursday afternoon and the service and food were top shelf. Ribeye steak was cooked to perfection. Brussels were excellent and the cornbread is actually GLUTEN FREE! Start with the deviled eggs or the street corn dip!

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RoCA

208 Court Ave, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerOpen LateAmericanCocktailsDeliveryTake AwayBarRestaurant
Perfect spot to kick back with unique cocktails and a rotating menu, especially before catching a show nearby!

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Brian Moe
Brian Moe
Delicious food options. Had the gluten free steak and mushroom flatbread. It was hold-your-breath-and-close-your-eyes delicious. Brussel sprouts were on point. Deconstructed nachos were amazing. And service was excellent, especially given the unexpected rush at the end of the night.

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Lachele's Fine Foods

2716 Ingersoll Ave, Des Moines, IA 50312, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayKid Friendly
Enjoy a clean and transparent cooking area where delicious dishes are prepared with care and a strong focus on special dietary needs.

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Katelin Tiernan
Katelin Tiernan
Super gluten free conscientious on top of DELICIOUS FOOD. I will be back over and over and can't recommend enough.

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Flying Mango

4345 Hickman Rd, Des Moines, IA 50310, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerAmericanDeliveryTake AwayKid FriendlyRestaurant
Fresh desserts and unique drinks make this spot a must-visit for a sweet treat and a refreshing sip while you wait for more.

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Dawn Collins
Dawn Collins
My daughter and I got some to go dessert and margaritas! The dessert was so fresh and tasty! We are both gluten-free and wanted to try some of their gluten-free dessert! So delicious! We also had a drink while we waited for our food! The mule was absolutely delicious! I believe it was strawberry. Just perfect! I can't wait to go back and have an entree!

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Simon's

5800 Franklin Ave, Des Moines, IA 50322, USA
Gluten-free options
LunchDinnerAmericanDeliveryTake Away
Expect warm hospitality and a personal touch from the owner, who’ll even share local tips for your visit.

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Hilda O'Dell
Hilda O'Dell
We visited Iowa from Missouri. After looking for a restaurant that offers gluten free options, we decided to dine here. We were blown away with the excellence of hospitality and food. Have you ever met someone that makes you feel like they are genuinely friendly and easy to talk to? The owner is that person and the amazing food was the icing on the cake. The owner even took some time to recommend places we should visit. Only thing missing is a Simon's in Missouri.

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Drake Diner

1111 25th St, Des Moines, IA 50311, USA
Gluten-free options
BreakfastLunchDinnerBrunchOpen LateAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant

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Jody Griggs
Jody Griggs
Not a dedicated gluten-free kitchen but the server made sure my breakfast had no toast with my gluten-free omelet. Tasty.

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Alba Restaurant

524 E 6th St, Des Moines, IA 50309, USA
Gluten-free options
LunchDinnerAmericanDeliveryTake AwayOutdoor SeatingRestaurant
Celebrate special moments here with top-notch service and a welcoming vibe that keeps customers coming back for more!

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Ashe
Ashe
Good GOLLY. I love this place. We went to celebrate getting through wedding planning and to celebrate a new job. Everyone was SO NICE. I mean 10/10 customer service. I have a severe gluten allergy and they were ON IT. Went so far above and beyond. The chef at the time (who was leaving) amazing and funny. The (what I can assume) Manager he was awesome too. Checking in making sure everything was perfect. And honestly this place is a 2.5 $ not 3. For what we got it was perfectly priced. We will be back!!!

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Applebee's Grill + Bar

3900 Merle Hay Rd, Des Moines, IA 50310, USA
Gluten-free options
BreakfastLunchDinnerOpen LateAmericanDeliveryTake AwayKid FriendlyRestaurant

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Alicia Andrews
Alicia Andrews
Always willing to listen for special orders, i.e. gluten free. Just need ask. Bartender is great and good conversation!-if you want to chat. Food hot and delicious. Combos husband and I can share with G.F restrictions.

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El Patio Mexican Restaurant

611 37th St, Des Moines, IA 50312, USA
Gluten-free options
LunchDinnerMexicanAmericanTake AwayOutdoor SeatingKid Friendly

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Pat Spain
Pat Spain
This restaurant has been a long time favorite for our family and friends. Nice variety of dishes, wonderful Mexican chocolate cake, flan for the gluten-free diets and decent prices. Depending on the night and seating, you may be waited on and served by the owners, who take time to interact and care about their customers.

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Harbinger

2724 Ingersoll Ave, Des Moines, IA 50312, USA
Gluten-free options
DinnerBrunchAmericanTake Away
Prepare for an outstanding culinary experience with artistic dishes and mind-blowing cocktails crafted by a talented team.

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J B
J B
I arrived for my second visit on Sept 6 2023, and ordered 3 dishes. One was with truffles. Gluten-free and vegetarian. However, after finishing the truffle with Leeks, I realized I was not feeling good. The rest of the night proceeded with full body hives, swollen lips, severe cold, diareah, vomit, and all extremities itching, and a plethora of experiences. I am not allergic to anything, so I suspect mold in the truffles and histamine response. Or a poisonous mushroom.

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