Top 39 Gluten-Free Sandwich Havens Across South Carolina

116 S Main St, Greenville, SC 29601, USA
Gluten Free IconCeliac friendly
BrunchAllergen FriendlyBreakfastDinnerKid FriendlyLunchOutdoor SeatingTake Away
This vibrant spot offers a safe gluten-free dining experience with dedicated fryers and a clearly marked menu. Guests enjoy a cozy atmosphere enhanced by live cello music and beautiful courtyard seating overlooking a lively, light-wrapped main street.
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1901 Ashley River Rd, Charleston, SC 29407, USA
Gluten Free Icon100% Dedicated Gluten-Free
Vegan OptionsAllergen FriendlyBakeryBreakfastBrunchCoffeeDairy Free OptionsDelivery
This cozy cafe offers a warm, relaxing atmosphere with adorable decor and a unique loft upstairs. Known for its entirely gluten-free menu, it provides a safe and welcoming space for those with gluten sensitivities, complemented by a friendly, chill vibe that enhances the dining experience.
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223 Sea Mountain Hwy, North Myrtle Beach, SC 29582, USA
Gluten Free IconCeliac friendly
Dedicated GF FryerBrunchLunchCafeDinnerBreakfastDairy FreeVegetarian
This small, cozy cafe with a fun beachy vibe offers a dedicated gluten-free kitchen ensuring safety for celiac diners. The staff are extremely friendly and knowledgeable, creating a welcoming atmosphere that makes it a top choice for those seeking safe, abundant gluten-free options.
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1229 Shine Ave, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
Allergen FriendlyDinnerKid FriendlyLunchOutdoor SeatingTake AwayDedicated GF FryerBread Items
This spot offers a dedicated gluten-free menu and a separate cooking space, ensuring a safe and flavorful experience. The well-educated staff provide excellent service, making it a welcoming retreat for those seeking plentiful gluten-free options in a lively, cozy atmosphere.
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1137 Morrison Dr, Charleston, SC 29403, USA
Gluten Free IconCeliac friendly
LunchDinnerDairy FreeAllergen FriendlyVeganVegetarianDedicated GF FryerTake Away
This lively burger joint offers a dedicated fryer for gluten-free options and gluten-free buns that hold up well. The knowledgeable, accommodating staff ensure a safe, enjoyable experience for those with gluten sensitivities, all within a fun, energetic atmosphere.
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Dedicated gluten-free menu

1110 N Ocean Blvd, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
LunchDinnerOpen LateDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items
Relaxed grill with extensive gluten-free menu and a dedicated fryer ensuring safe, delicious meals.
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Dedicated gluten-free menu

4954 Hwy 17 S, North Myrtle Beach, SC 29582, USA
Gluten Free IconCeliac friendly
SeafoodAllergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingTake Away
Waterfront restaurant with dedicated gluten-free menu and manager-led allergy care ensuring safe, tasty meals.
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Dedicated gluten-free menu

209 S Main St, Greenville, SC 29601, USA
Gluten Free IconCeliac friendly
BurgersDinnerPet FriendlyKid FriendlyLunchOutdoor SeatingTake AwayGF Menu
This lively spot offers a fun atmosphere with both indoor and outdoor seating spaced for comfort, making it a great and safe place to eat gluten-free. The attentive service and dedicated gluten-free milkshake blender enhance the experience for those with gluten sensitivities.
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1320 Celebrity Cir Unit 195, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
LunchDinnerOpen LateBurgersDeliveryTake AwayPet FriendlyOutdoor Seating
This spot offers an industrial, modern decor with a vibrant atmosphere, featuring a dedicated gluten-free kitchen that ensures safe dining for celiac guests. The warm, courteous service enhances the inviting setting, making it a top choice for gluten-free diners.
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38 Shelter Cove Ln, Hilton Head Island, SC 29928, USA
Gluten Free IconCeliac friendly
SeafoodDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingDedicated GF FryerBeer
Perched atop with breathtaking water views, this spot offers a lovely open-air atmosphere perfect for gluten-free diners. A dedicated fryer ensures safe fried seafood, blending upscale dining with casual comfort in a welcoming setting.
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214 N Cedar St, Summerville, SC 29483, USA
Gluten Free IconCeliac friendly
AmericanBrunchAllergen FriendlyCoffeeKid FriendlyLunchOutdoor SeatingTake Away
Set in a charming upcycled old home with southern chic decor and inviting porches, this cozy cafe offers a dog-friendly outdoor patio and a sunroom with a great aesthetic. The friendly staff and clean, modern atmosphere create a welcoming space ideal for gluten-free diners.
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1055 Johnnie Dodds Blvd #100, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
AmericanBrunchCoffeeDeliveryKid FriendlyLunchOutdoor SeatingTake Away
Charming café with extensive gluten-free options and a cozy, California vibey atmosphere.
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7931 N Kings Hwy #140, Myrtle Beach, SC 29572, USA
Gluten Free IconAccommodating Gluten-Free
GrillBurgersBreakfastAllergen FriendlyBrunchCoffeeKid FriendlyLunch
This charming brunch spot features a lively, warm atmosphere and a comfortable patio with shade and fans, creating an inviting setting for those seeking gluten-free dining. Attentive service enhances the experience, making it a standout choice for gluten-free guests.
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354 Coleman Blvd, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
BreakfastLunchBrunchCafeTake AwayPet FriendlyOutdoor SeatingKid Friendly
This coffee shop offers a cozy, neighborly vibe with a cheery clementine exterior and a large live oak tree shading the outdoor deck. It stands out as a welcoming spot for gluten-free options, featuring a variety of delicious pastries and a friendly, efficient staff.
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4856 US-17, North Myrtle Beach, SC 29582, USA
Gluten Free IconAccommodating Gluten-Free
Wine BarLunchBrunchBreakfastVegan OptionsAllergen FriendlyDinnerKid Friendly
Set against a beautiful lake backdrop, this spacious eatery features a delightful patio with roll-down shades, fans, and misters, creating a comfortable outdoor dining experience. The gorgeous decor with purposeful beams and angles complements a vibrant atmosphere, making it an ideal spot for those seeking gluten-free dining in a welcoming setting.
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504 Mill St, Mt Pleasant, SC 29464, USA
Gluten Free IconAccommodating Gluten-Free
SushiSeafoodAmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDinner
Perched atop a quaint rooftop with incredible views of the salt marsh and Shem Creek, this tavern offers a serene and comfortable atmosphere enhanced by fairy-lit ceilings and casual decor. The attentive staff ensures a safe and welcoming environment for gluten-free diners, making it a standout choice for those with gluten sensitivities.
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6 E Washington St, Greenville, SC 29601, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchOpen LateSandwichesDeliveryTake Away
This cozy deli offers a peaceful courtyard retreat with a clean, inviting atmosphere enhanced by '80s and '90s tunes. It's a gluten-free haven in Greenville, known for its exceptionally chewy and tasty gluten-free bagels and a friendly, accommodating staff.
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225 Calhoun St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
Allergen FriendlyDairy Free OptionsDeliveryKid FriendlyLunchOutdoor SeatingTake AwayVegan Options
Step into a cozy spot bursting with 80s and 90s memorabilia, creating a nostalgic museum vibe. The laid-back, inviting atmosphere and friendly, knowledgeable service make it a great choice for those seeking gluten-free dining in a charming, character-filled setting.
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30 Orchard Park Dr Suite 7, Greenville, SC 29615, USA
Gluten Free IconCeliac friendly
GrillDairy Free OptionsDinnerOpen Late NightLunchTake AwayDedicated GF FryerBread Items
This lively spot offers a dedicated gluten-free menu with separate fryers ensuring safe, flavorful options. The fun atmosphere features pool tables, darts, board games, and multiple TVs, making it a gluten-friendly haven for groups and families alike.
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3042 Howard Ave, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastBrunchCoffeeDairy Free OptionsKid FriendlyLunchOutdoor SeatingTake Away
This charming, southern-style restaurant features a warm, inviting atmosphere with a unique ceiling display and a lovely patio. Guests appreciate the friendly, welcoming staff and the clean, cozy setting, making it a great choice for those seeking gluten-free dining options.
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435 William Hilton Pkwy suite g, Hilton Head Island, SC 29926, USA
Gluten Free IconCeliac friendly
BrunchLunchDinnerBreakfastBread ItemsSandwichesDessertsFries
This inviting spot offers a casual, friendly setting with a mom and pop diner vibe and a cute ice cream parlor atmosphere. Known for its extensive, clearly marked gluten-free options, it provides confident dining for those with gluten sensitivities alongside friendly, accommodating service.
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North 1371, US-17, Little River, SC 29566, USA
Gluten Free IconAccommodating Gluten-Free
BakeryBreakfastBrunchKid FriendlyLunchTake AwayBread ItemsDesserts
Charming bakery with a wide gluten-free selection and a clean, inviting space offering delicious treats.
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3246 Forest Dr, Columbia, SC 29204, USA
Gluten Free IconAccommodating Gluten-Free
Take AwayDessertsLunchSandwichesBreakfastBrunchPet FriendlyOutdoor Seating
This lively spot offers a warm, welcoming atmosphere with pet-friendly outdoor seating, creating an inviting charm for gluten-free diners. The staff is notably patient and helpful, providing thorough guidance on gluten-free options, making it a hospitable oasis for those with dietary needs.
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171 E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsBrunchBreakfastKid FriendlyOutdoor SeatingTake AwayBread ItemsSandwiches
This lively spot features a spacious dining area with indoor and outdoor seating, creating a welcoming atmosphere enhanced by pleasant music. Known for its full gluten-free menu and excellent service, it offers a fun and accommodating environment for gluten-free diners.
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9500 Dorchester Rd, Summerville, SC 29485, USA
Gluten Free IconAccommodating Gluten-Free
Grab & GoKid FriendlyLunchTake AwayVegetarian OptionsVegan OptionsBread ItemsSandwiches
Lively sandwich shop with gluten-free options and a clean, organized environment despite high traffic.
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6809 State Park Rd, Travelers Rest, SC 29690, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastBrunchLunchOutdoor SeatingVegan OptionsVegetarian OptionsBread ItemsSandwiches
This charming spot features a laid-back vibe with eclectic, spacious outdoor seating ideal for groups seeking a relaxed atmosphere. Known for its fresh bakery goods with gluten-free options, it offers a welcoming setting for those prioritizing gluten-free dining experiences.
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8014 N Kings Hwy, Myrtle Beach, SC 29572, USA
Gluten Free IconCeliac friendly
BreakfastLunchBrunchBakeryCafeDeliveryTake AwayOutdoor Seating
Step into a charming space where French bakery ambiance meets vibrant cafe vibes, featuring a beautiful interior reminiscent of a French bakery. The staff is known for their attentive service and thoughtful accommodations, ensuring a welcoming experience for those seeking gluten-free options in a delightful setting.
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334 E Bay St Ste H, Charleston, SC 29401, USA
Gluten-free options
Salad BarLunchKid FriendlyBread ItemsSandwichesDeliveryTake AwayDesserts
This deli offers a festive and comforting atmosphere with plenty of seating and easy parking, enhancing the casual dining experience. Guests appreciate the fast, friendly service and the availability of excellent gluten-free options including toasted gluten-free bread.
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1034 William Hilton Pkwy, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsVegan OptionsBakeryVegetarian OptionsBread ItemsDessertsSandwichesDelivery
This charming spot offers a fun, family-friendly atmosphere with colorful local art and a cozy fire pit perfect for groups. Its welcoming vibe and creative setting make it an ideal destination for those seeking a delightful gluten-free experience.
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103 Old Boiling Springs Rd, Greenville, SC 29615, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesDeliveryTake AwayOutdoor SeatingKid FriendlyBread Items
This spot offers a spotless dining room and quiet music, creating an ideal setting for those seeking a gluten-free dining experience. The staff's professional and attentive service ensures careful handling of dietary needs, enhancing comfort and safety.
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125 Rolling Hills Cir Unit C, Easley, SC 29640, USA
Gluten Free IconAccommodating Gluten-Free
LunchAllergen FriendlyDairy Free OptionsGrab & GoKid FriendlyOutdoor SeatingTake AwayVegan Options
This spot offers a quiet atmosphere ideal for clear communication when ordering gluten-free options. Known for its thoughtful gluten-free bun, it caters attentively to those with gluten allergies, complemented by friendly staff and attentive service.
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1067 Tiger Blvd # 50, Clemson, SC 29631, USA
Gluten Free IconAccommodating Gluten-Free
LunchGrab & GoKid FriendlyTake AwayVegetarian OptionsVegan OptionsBread ItemsSandwiches
This spot is a go-to for gluten-free diners, with staff who are friendly, helpful, and attentive to allergies. Their gluten-free bread option is highly praised, making it a reliable choice for those with gluten intolerance seeking a safe and satisfying experience.
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2019 Middle St, Sullivan's Island, SC 29482, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastCoffeeLunchBread ItemsSandwichesDinnerBrunchDelivery
This vibrant coastal spot offers a laid-back, open-air beach vibe with cozy heaters for a romantic, warm atmosphere. Known for its dedicated gluten-free bread toaster, it ensures a safe and enjoyable experience for gluten-free guests in a peaceful, friendly setting.
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1600 Farrow Pkwy, Myrtle Beach, SC 29577, USA
Gluten-free options
ItalianPizzaDeliveryDinnerLunchOutdoor SeatingTake AwayVegetarian Options
Cozy eatery with extensive gluten-free menu featuring pizza, Stromboli, and keto-friendly options.
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1222 Alice Dr, Sumter, SC 29150, USA
Gluten Free IconAccommodating Gluten-Free
LunchGrab & GoKid FriendlyTake AwayVegetarian OptionsVegan OptionsBread ItemsSandwiches
This family-friendly spot excels in meticulous gluten-free preparation, with staff ensuring no cross-contamination through thorough cleaning and glove changes. The safe assembly area and attentive service create a reliable environment for gluten-sensitive guests.
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1000 S Commons Dr, Myrtle Beach, SC 29588, USA
Gluten-free options
BreakfastLunchDinnerSandwichesDeliveryTake AwayOutdoor SeatingKid Friendly
This deli features an open, clean atmosphere with a friendly, speedy service ideal for a satisfying lunch. The staff's attentiveness to gluten-free needs ensures a safe and welcoming environment for those with gluten sensitivities or celiac disease.
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8983 University Blvd # 101, North Charleston, SC 29406, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
This sub shop maintains a clean, tidy atmosphere and demonstrates exceptional care for gluten-free diners, including dedicated utensils to prevent cross contamination. Their staff provide attentive, courteous service, ensuring a safe and comfortable experience for those with gluten allergies.
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1598 Sandifer Blvd, Seneca, SC 29672, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerSandwichesDeliveryTake AwayOutdoor SeatingKid Friendly
This spot offers a clean, relaxed atmosphere with music at a comfortable volume, creating a welcoming environment. The staff is helpful and knowledgeable about gluten-free options, ensuring a safe and pleasant dining experience for those with dietary needs.
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2222 Augusta St #6, Greenville, SC 29605, USA
Gluten Free IconAccommodating Gluten-Free
RestaurantLunchDinnerVegetarianVeganDairy FreeAllergen FriendlyTake Away
Clean, welcoming spot with accommodating staff ensuring safe preparation for gluten free needs.
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Gluten-free options are marked

310d Azalea Square Blvd, Summerville, SC 29483, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerGrab & GoKid FriendlyTake AwayVegetarian OptionsVegan OptionsBread Items
This sandwich shop offers a carefully maintained environment with staff who take stringent cross-contamination precautions for gluten-free diners. The focus on clean utensils and slicers ensures a safe and accommodating experience for those with gluten allergies.
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272 Robert Smalls Pkwy #340, Beaufort, SC 29906, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
Busy sub shop with gluten-free Udi's rolls and fresh meats in a cool atmosphere.
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2676 Church St, Conway, SC 29526, USA
Gluten Free IconAccommodating Gluten-Free
DeliveryGrab & GoKid FriendlyLunchTake AwayVegetarian OptionsVegan OptionsBread Items
This sub shop offers a friendly atmosphere with staff who prioritize safety and care for gluten-free guests. Their team ensures a clean, cross-contamination-free environment, making it a trusted choice for those with celiac disease seeking a welcoming dining experience.
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7001 St Andrews Rd, Columbia, SC 29212, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
This spot offers a clean, fresh environment with a well-maintained dining area and friendly, polite service. Its locally owned vibe adds a personal touch, making it a welcoming place for those seeking a gluten-free dining experience.
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1141 Knox Ave, North Augusta, SC 29841, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
Clean, comfortable sub shop with gluten free bread options and dedicated staff attentive to dietary needs.
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1714 Gold Hill Rd, Fort Mill, SC 29708, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
This well-kept sandwich spot offers a welcoming atmosphere ideal for those seeking gluten-free options. Known for its fresh, bold flavors, it provides a satisfying experience with gluten-free choices that cater thoughtfully to dietary needs.
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430 William Hilton Pkwy Suite 201, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
Well-maintained sandwich shop with gluten free sub rolls and fresh, tasty ingredients over greens.
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1221 Chapin Rd, Chapin, SC 29036, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesDeliveryTake AwayPet FriendlyKid FriendlyBread Items
This welcoming spot ensures a safe and contamination-free environment for gluten-free diners, with staff taking meticulous care like changing gloves and using dedicated utensils. The inviting atmosphere makes it a comfortable place to enjoy a meal with confidence.
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280 W Coleman Blvd A, Mt Pleasant, SC 29464, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerCafeSandwichesDeliveryTake AwayKid FriendlyBread Items
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581 By-pass 72 NW, Greenwood, SC 29649, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesDeliveryTake AwayPet FriendlyKid FriendlyBread Items
This spot offers a carefully maintained environment with staff who ensure utensils and surfaces are thoroughly cleaned for gluten-free preparation. The attentive service and dedicated gluten-free cleaning process create a safe, welcoming atmosphere for those with celiac disease.
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1915 E Main St Suite 2, Spartanburg, SC 29307, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSandwichesGrab & GoDeliveryTake AwayPet FriendlyKid Friendly
This sub shop offers a gluten-free sub option catering to those with Celiac disease, though availability may vary. The service is generally excellent, with a welcoming atmosphere that supports customers seeking gluten-free choices.
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