Top 25 Gluten-Free Spots to Explore in Seneca

1598 Sandifer Blvd, Seneca, SC 29672, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerSandwichesDeliveryTake AwayOutdoor SeatingKid Friendly
This spot offers a clean, relaxed atmosphere with music at a comfortable volume, creating a welcoming environment. The staff is helpful and knowledgeable about gluten-free options, ensuring a safe and pleasant dining experience for those with dietary needs.

People are saying
View more
Brandon da Painter
Brandon da Painter
They are always helpful with the gluten free options

Menu
View menu

125 N Townville St, Seneca, SC 29678, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayOutdoor Seating
This locally owned spot offers a nostalgic, cozy atmosphere with a lively yet tempered vibe enhanced by jazz and a downtown setting. The gluten-friendly environment is supported by careful staff ensuring a safe and welcoming experience for those with gluten sensitivities.

People are saying
View more
Leticia Chaparro
Leticia Chaparro
Super cute restaurant! The service made you feel like a home town place. The food was great, with vegetarian AND gluten free options! I had the ginger chicken sandwich and cheesy potato soup. Yummy!!! My husband had the Cuban and said it was pretty good. But if you like peanut butter the pie is a MUST HAVE. So glad we stopped in. 😁

Menu
View menu

13434 Clemson Blvd, Seneca, SC 29678, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerMexicanAmericanTacosDeliveryTake AwayPet Friendly
This vibrant spot features a spacious seating and lively bar area, creating an energetic atmosphere. Multiple TVs enhance the setting, making it a dynamic place to gather, though gluten-free options may not be reliably available as advertised.

People are saying
View more
Andrew Cooper
Andrew Cooper
The food was mid, service was okay, atmosphere was dead, food take almost an hour despite being THE ONLY in the restaurant. We had to listen to foul language beside us the entire time we Waited on our food. Menu said gluten free options and as you may come to expect we in fact did not receive gluten free options. Thank you so help me GOD.

Menu
View menu

1727 Blue Ridge Blvd, Seneca, SC 29672, USA
Gluten Free IconAccommodating Gluten-Free
DinnerItalianDeliveryTake AwayOutdoor SeatingKid FriendlyLunch
This Italian eatery features a large covered patio with umbrella-shaded tables, offering a relaxed and welcoming atmosphere ideal for gluten-free diners. They take celiac disease seriously, providing a dedicated gluten-free menu and excellent gluten-free pizza that many patrons enjoy.

People are saying
View more
Lindsey Martorana
Lindsey Martorana
If you’re gluten free, just stick with the pizza. The rest of the food was blah. I originally wanted a pizza, but the waitress told me the scallops “changed her life” so I ordered them only to be disappointed. 4 medium-sized, rubbery, over-cooked scallops showed up on my plate drizzled with some balsamic glaze that did not go well at all, and because I wanted a salad, my meal alone cost $50. HUGE waste of money! The atmosphere and service (besides the car-salesman pressure) was good.

Menu
View menu

106 Ram Cat Alley, Seneca, SC 29678, USA
Gluten-free options
BakeryDeliveryTake AwayDesserts
Nestled in a historic alley, this bakery offers a welcoming atmosphere for gluten-free guests with specialty cakes crafted to delight those with dietary restrictions. Their expert bakers create beautifully decorated, allergy-sensitive cakes, ensuring a joyful and safe dessert experience.

People are saying
View more
ELE Everyone love everyone
ELE Everyone love everyone
Great bakery, PERIOD. We tried both gluten free and not gluten free items. Cookies, cupcakes, and Lava brownies are amazing. Love the uniqueness of their creations. We are from the northeast and use to sugar load acidic nastiness. Hats off to the baker for making desserts that didn’t give us indigestion! Thank you for a delicious experience!

Menu
View menu

273 Market St, Seneca, SC 29678, USA
Gluten-free options
LunchDinnerItalianPizzaDeliveryTake AwayKid Friendly
This spot offers a dual ambiance with a darker, booth-lined area free of TVs and a lively, well-lit bar featuring five screens, creating a comfortable setting for those seeking gluten-free dining. The attentive service enhances the experience, making it a fun and accommodating pizza place for gluten-free options.

People are saying
View more
Wynne VanBuskirk
Wynne VanBuskirk
Great experience eating here. There are two parts to the restaurant, one darker with mostly (?) booths and I don’t think any tvs, and the bar area, well lit with 5 tvs playing a variety of things (Fail Army, animal videos, and sports). Waiter was on top of things, remembered my somewhat complicated order without writing anything down. He remembered previous customers and what they ordered, and was cordial and warm with everyone. The food was very good for a pizza joint. I could have done with less iceberg lettuce and more romaine in my Greek salad, but otherwise no complaints. Gluten Free pizza crust was excellent! Nice and thin and not too sweet. My husband had a pizza with sausage, jalapeño and pineapple (on a regular rust) which he said was excellent. We were in a hurry tonight, so sadly, no dessert. Great place for pizza!

Menu
View menu

12019 N Radio Station Rd, Seneca, SC 29678, USA
Gluten-free options
LunchDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyRestaurantDinner
This intimate spot features a small patio with shaded outdoor tables, creating a pleasant and friendly environment ideal for gluten-free diners. The staff is known to be very awesome and accommodating, making it a staple lunch destination with plenty of gluten-free options available.

People are saying
View more
Suzanne King
Suzanne King
I went here for the first time with school friends for lunch. When I stepped to the register to place my order which was the special of the day "the Smokehaus". It's pulled pork, fennel slaw, Chipotle BBQ sauce, cheddar cheese and fried onions. I ordered mine without the wrap because I am gluten free. The girl asked if I wanted it on a bowl of rice or bowl of lettuce. I answered her with neither just a bowl. She said sure. She then repeated my order to a manager or someone in charge. That person looked directly at me and said "no. We don't do substitutions." She was extremely rude to me. She then turned around and left the counter girls in limbo. I replied that I wouldn't order anything. I wasn't substituting anything just deleting.

Menu
View menu

700 By Pass, US-123, Seneca, SC 29678, USA
Gluten-free options
LunchDinnerAsianSushiDeliveryTake AwayOutdoor SeatingKid Friendly
This spot offers a huge, heated outdoor area with fire pits and big heaters, creating a comfortable and dog-friendly space ideal for those seeking a cozy dining experience. The inviting atmosphere enhances enjoyment for guests preferring gluten-free options.

People are saying
View more
Jennifer Kate
Jennifer Kate
The food was great, and the atmosphere was delightful. However, it was chilly inside, so we opted for the more comfortable outdoor seating. The waitresses seemed rushed and strained to be polite. They would quickly check if we needed anything but then hurry off right away. They offered a Gluten Free menu which was nice.

Menu
View menu

115 Rochester Hwy, Seneca, SC 29672, USA
Gluten-free options
BakeryDeliveryGrocery Store
This market offers a well-organized, clean layout that makes shopping for gluten-free products easy and convenient. With a great variety of gluten-free options and a friendly, accommodating staff, it stands out as a top choice for those with gluten sensitivities.

People are saying
View more
Jennifer Kate
Jennifer Kate
Loved how everything was in order & they have came a long way with making available the gluten free brands that actually taste good. I would like to see more dairy free options and better labeling.

Menu
View menu

1612 Sandifer Blvd, Seneca, SC 29678, USA
Gluten-free options
BreakfastLunchDinnerGrab & GoDeliveryPet FriendlyOutdoor SeatingKid Friendly
This location offers a dedicated drive-through lane enhancing convenience for gluten-free customers. While service is generally friendly, some guests note inconsistent accommodations for gluten allergies, making it less reliable compared to other nearby locations known for better gluten-free support.

People are saying
View more
Timothy Ahl
Timothy Ahl
I started eating grilled because I am going gluten free. And 20 min after I ate the food I vomited. When I called to file a complaint. They just said there is nothing we can do. Did not know chic fila rolled that way. Honestly extremely disappointed. Maybe it's just the Seneca location STEER CLEAR go to Clemson instead at least they care never had such bad service.

Menu
View menu

400 S Fairplay St, Seneca, SC 29678, USA
Gluten-free options
BreakfastLunchBrunchAmericanDeliveryTake AwayKid FriendlyRestaurant
This cozy cafe offers an inviting atmosphere perfect for frequent visits. Its warm, homey setting makes it a beloved spot for breakfast, providing a comfortable space to enjoy your meal multiple times a week.

People are saying
View more
Glenda Pitts
Glenda Pitts
We love this place for breakfast. We are here usually 2 or 3 times a week. I would like to know if the grits are gluten free, I have recently started a gluten free diet.

Menu
View menu

122 Ram Cat Alley, Seneca, SC 29678, USA
Gluten-free options
DeliveryTake AwayOutdoor SeatingRestaurantKid Friendly
This spot offers a mellow, cool vibe with a lively bar atmosphere enhanced by outdoor bands, creating a relaxing yet vibrant setting. The venue is smoke-free, making it a comfortable choice for those seeking a gluten-free friendly environment with attentive service.

People are saying
View more
Ashley Bednar
Ashley Bednar
Very tasty food and a variety of gluten free items on their gluten free menu.

Menu
View menu

922 By Pass, US-123, Seneca, SC 29678, USA
Gluten Free IconAccommodating Gluten-Free
PizzaDeliveryTake Away
This lively spot offers a welcoming atmosphere perfect for families and those seeking gluten-free options. Known for its gluten-free pizzas that delight with quality and taste, it provides a comfortable setting ideal for a satisfying, safe dining experience.

People are saying
View more
Jennifer Jefferson
Jennifer Jefferson
This Dominos is on point! It is my favorite Dominos in our are. My order was a gluten free with extra cheese and extra pepperoni, well done, square cut. By far my favorite place to get gluten free pizza. Wings are also amazing from here. Highly recommend.

Menu
View menu

807 By Pass 123 #16, Seneca, SC 29678, USA
Gluten-free options
BreakfastLunchDinnerBrunchBakeryOpen LateCafeCocktails
This cozy cafĂ© features repurposed church pews and a welcoming, calming ambience perfect for a gluten-free dining experience. With gluten-free, vegetarian, and vegan-friendly options crafted from locally grown ingredients, it’s an ideal spot for health-conscious guests seeking fresh, flavorful meals.

People are saying
View more
Ginny Williams
Ginny Williams
We stopped here for coffee and a light breakfast and it was absolutely charming. The staff was welcoming and we loved the unique coffee options. Each of us got the avocado toast, but two of us got the gluten-free bread and it was all delicious. I appreciated that they slightly mashed up the avocado on the toast so it didn’t slide all around!

Menu
View menu

403 E Main St, Seneca, SC 29678, USA
Gluten-free options
LunchDinnerPizzaDeliveryTake AwayOutdoor SeatingKid Friendly
This spot is renowned for its fantastic gluten-free crust option, making it a top choice for those with gluten sensitivities. The inviting atmosphere complements the memorable dining experience praised by many gluten-free diners.

People are saying
View more
Vanessa Condon
Vanessa Condon
G's is my new go to pizza place!!! Their marinara/pizza sauce is THE BEST I've ever had. They also have a fantastic gluten free crust option. I wish they cooked the gf crust a little more, but I always enjoy it. We always get the gf quatro carne (see picture attached). If I'm honest, the service can be hit or miss as they are expanding to meet the demand. But I've never had a bad experience!! I've just had to wait some times.

Menu
View menu

13444 Clemson Blvd, Seneca, SC 29678, USA
Gluten-free options
BakeryDeliveryTake AwayDesserts
This charming store features a vibrant pink interior, creating a playful and cheerful atmosphere perfect for those seeking a delightful gluten-free experience. The setting complements the wonderful assortment of gluten-free cookies, making it a sweet spot for visitors.

People are saying
View more
Susan Meindertsma
Susan Meindertsma
LOVE this place! Very yummy gluten free cookies, as well as a wonderful assortment of others. And it's PINK, my favorite color!

Menu
View menu

1026 By Pass 123 Ste B, Seneca, SC 29678, USA
Gluten-free options
LunchDinnerSandwichesDeliveryOutdoor SeatingKid FriendlyBread Items

People are saying
View more
Jeffrey Davis
Jeffrey Davis

Menu
View menu

277 Market St, Seneca, SC 29678, USA
Gluten-free options
BreakfastCafeDeliveryTake AwayOutdoor SeatingKid Friendly
This coffee shop features a friendly, cozy atmosphere with comfortable seating and calming decor, making it perfect for relaxing, working, or meeting friends. The charming ambience and friendly staff create an inviting space ideal for enjoying a good coffee while unwinding or socializing.

People are saying
View more
Lisa Kieffer
Lisa Kieffer
Good coffee and friendly staff. Cuter than expected ambience for reading, writing, or meeting with friends. I appreciated that they had some prepackaged gluten free snacks.

Menu
View menu

1026 By Pass 123 E Street, Seneca, SC 29678, USA
Gluten-free options
LunchDinnerOpen LatePizzaDeliveryTake AwayKid Friendly
This venue provides a unique dining experience with a focus on accommodating gluten-free needs. The atmosphere supports a comfortable setting for enjoying specialty gluten-free options, ensuring a memorable visit for those seeking gluten-conscious choices.

People are saying
View more
Sarah Tracy
Sarah Tracy

Menu
View menu

514 US-123, Seneca, SC 29678, USA
Gluten-free options
LunchDinnerAmericanDeliveryTake AwayOutdoor SeatingKid Friendly

People are saying
View more
Julio Broome
Julio Broome

Menu
View menu

103 State Rd S-37-135, Seneca, SC 29672, USA
Gluten-free options
LunchDinnerMexicanTake AwayOutdoor SeatingKid Friendly

People are saying
View more
Roger Wolfgang
Roger Wolfgang

Menu
View menu

119 Ram Cat Alley, Seneca, SC 29678, USA
Gluten-free options
DinnerDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant

People are saying
View more
Kami Johnson
Kami Johnson

Menu
View menu

1290 State Rd S-37-15, Seneca, SC 29672, USA
Gluten-free options
LunchDinnerBrunchAmericanDeliveryTake AwayOutdoor SeatingKid Friendly

People are saying
View more
David Place
David Place

Menu
View menu

1109-A Jennings Ave, Seneca, SC 29678, USA
Gluten-free options
Ice CreamDeliveryTake Away

People are saying
View more
Christopher Heilman
Christopher Heilman

Menu
View menu

273 Market St, Seneca, SC 29678, USA
Gluten-free options
Ice CreamDeliveryTake AwayKid Friendly

People are saying
View more
Hillary Gates
Hillary Gates

Menu
View menu

© 2025 Atly - Your Local Guide to Gluten-Free Dining