Top 50 Gluten-Free Spots for Exquisite Cocktails Across South Carolina

1875 N Hwy 17, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
DinnerLunchDairy Free OptionsAllergen FriendlyKnowledgeable StaffDedicated GF FryerSeparate GF MenuAmerican
This upscale spot offers a warm, inviting atmosphere ideal for relaxed dining or special occasions, with a dog-friendly patio and multiple TVs for sports fans. Its attentive, friendly staff and commitment to gluten-free dining create a confident, enjoyable experience for those with gluten sensitivities.
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Dedicated gluten-free menu

116 S Main St, Greenville, SC 29601, USA
Gluten Free IconCeliac friendly
BrunchAllergen FriendlyBreakfastDinnerKid FriendlyLunchOutdoor SeatingTake Away
This vibrant spot offers a safe gluten-free dining experience with dedicated fryers and a clearly marked menu. Guests enjoy a cozy atmosphere enhanced by live cello music and beautiful courtyard seating overlooking a lively, light-wrapped main street.
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Gluten-free options are marked

82 Wentworth St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
GF MenuDedicated GF FryerAllergen FriendlyBreakfastLunchDinnerCocktailsCasual
This hip, upscale spot features a bright, beachy decor and a cool outdoor courtyard, creating a lively yet charming atmosphere. With a dedicated gluten-free fryer and allergy-aware service, it’s perfect for those seeking safe, gluten-free dining in a welcoming setting.
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Gluten-free options are not marked

1137 Morrison Dr, Charleston, SC 29403, USA
Gluten Free IconCeliac friendly
LunchDinnerDairy FreeAllergen FriendlyVeganVegetarianDedicated GF FryerTake Away
This lively burger joint offers a dedicated fryer for gluten-free options and gluten-free buns that hold up well. The knowledgeable, accommodating staff ensure a safe, enjoyable experience for those with gluten sensitivities, all within a fun, energetic atmosphere.
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Dedicated gluten-free menu

711 Gervais St, Columbia, SC 29201, USA
Gluten Free IconCeliac friendly
GrillBurgersCocktailsAmericanAllergen FriendlyDairy Free OptionsDeliveryDinner
This spacious spot offers a pet-friendly porch and a lively bar with numerous TVs, creating a vibrant atmosphere. It stands out as a gluten-free haven with a dedicated fryer and a wide variety of tasty gluten-free options, ensuring a safe and enjoyable dining experience.
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Gluten-free options are marked

304 King St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
LunchDinnerGF Options Marked on MenuDedicated GF FryerKnowledgeable StaffVegetarian OptionsDairy Free OptionsVegan Options
This vibrant spot offers a gluten-free dining experience with a kitschy-modern interior and a chill, nostalgic vibe. Guests enjoy a welcoming atmosphere where all dishes, including tacos and falafel, are gluten free, complemented by fresh-squeezed cocktails and attentive, knowledgeable service.
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Gluten-free options are marked

320 Wingo Way #100, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
LunchDinnerBrunchAmericanSeafoodDeliveryTake AwayPet Friendly
This venue captivates with its rustic charm and low country coastal decor, creating an intimate yet inviting atmosphere ideal for gluten-free diners. The staff is attentive and knowledgeable, ensuring excellent gluten-free accommodations and a welcoming Southern ambiance.
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2901a Devine St, Columbia, SC 29205, USA
Gluten Free IconCeliac friendly
MexicanCocktailsAllergen FriendlyBrunchDinnerKid FriendlyLunchOutdoor Seating
This modern eatery offers a relaxed, chill atmosphere with a pleasant outdoor dining area, making it an inviting spot for those seeking gluten-free options. The staff is knowledgeable and conscientious, ensuring a safe and enjoyable experience for gluten-sensitive guests.
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Gluten-free options are marked

31 J C Long Blvd, Isle of Palms, SC 29451, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodCocktailsAmericanBrunchBreakfastAllergen FriendlyDairy Free OptionsDinner
This spot offers a laid-back, family-friendly atmosphere with authentic Southern hospitality. The shaded, dog-friendly back patio enhances its welcoming charm, making it a comfortable choice for those seeking a gluten-free dining experience with attentive service and accommodating staff.
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Gluten-free options are marked

1000 William Hilton Pkwy Suite J6, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchVeganCafeMexicanCocktails
This vibrant eatery offers a calm, inviting atmosphere with fantastic outdoor seating, making it a welcoming spot for gluten-free diners. Known for its allergy-friendly practices and careful food handling, it ensures a safe and enjoyable experience for those with gluten intolerance.
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4840 Forest Dr, Columbia, SC 29206, USA
Gluten Free IconCeliac friendly
BreakfastLunchDinnerBrunchAmericanCocktailsDeliveryTake Away
This spot features an upbeat and inviting atmosphere with an excellent gluten-free selection clearly marked for celiac diners. The knowledgeable service and diverse options ensure a satisfying experience for those seeking gluten-free meals.
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Gluten-free options are marked

340 King St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsAsianDairy Free OptionsDinnerLunchTake AwayDeliveryOutdoor Seating
This spot offers a cool, vibrant vibe with a gorgeous, slightly dark interior perfect for day or night. The awesome atmosphere and friendly, accommodating staff create a welcoming setting, enhanced by a dedicated gluten-free menu ensuring a safe and enjoyable experience.
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1301 Main St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
MexicanCocktailsDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingVegan Options
This lively spot offers a fun and energetic atmosphere with plenty of bar seating and TVs for sports fans, plus an inviting outdoor space. It stands out for its clearly marked gluten-free options and attentive service, making it a stress-free choice for gluten-free diners.
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Gluten-free options are marked

3098 Deville St, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
SushiCocktailsVegan OptionsAllergen FriendlyAsianDairy Free OptionsDinnerKid Friendly
This chic spot offers a cosmopolitan atmosphere perfect for a date night, with a bumpin' vibe and attentive service that respects gluten-free needs. The upscale yet cool setting creates an inviting experience for those seeking quality and ambiance without compromise.
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Dedicated gluten-free menu

171 E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsBrunchBreakfastKid FriendlyOutdoor SeatingTake AwayBread ItemsSandwiches
This lively spot features a spacious dining area with indoor and outdoor seating, creating a welcoming atmosphere enhanced by pleasant music. Known for its full gluten-free menu and excellent service, it offers a fun and accommodating environment for gluten-free diners.
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250 Mill St PW3151, Taylors, SC 29687, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchAmericanTake AwayOutdoor SeatingKid FriendlyDelivery
Set in a reclaimed historic mill, this spot offers a rustic yet tasteful interior with an open kitchen and a fun, funky atmosphere. The eclectic vibe and massive bar with a sliding ladder create a lively setting ideal for those seeking gluten-free dining in a unique environment.
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1034 William Hilton Pkwy, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsVegan OptionsBakeryVegetarian OptionsBread ItemsDessertsSandwichesDelivery
This charming spot offers a fun, family-friendly atmosphere with colorful local art and a cozy fire pit perfect for groups. Its welcoming vibe and creative setting make it an ideal destination for those seeking a delightful gluten-free experience.
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Gluten-free options are marked

112 Trade St, Greer, SC 29651, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchCafeAmericanDeliveryTake Away
This lively spot offers an upscale yet welcoming atmosphere with great art adorning the walls, creating a cozy and fun environment ideal for gluten-free diners. The attentive service and expertly prepared dishes ensure a delightful experience with several gluten-free options available.
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7811 Rivers Ave, North Charleston, SC 29406, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateCocktailsDeliveryTake AwayOutdoor SeatingKid Friendly
Step into a tropical island escape with high ceilings and lush plants creating a vacation-like mood. The laid-back atmosphere and live nighttime music offer a relaxing setting, while the knowledgeable staff ensure a safe gluten-free dining experience.
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Dedicated gluten-free menu

112 N Main St, Anderson, SC 29621, USA
Gluten Free IconAccommodating Gluten-Free
Wine BarSeafoodCocktailsAmericanAllergen FriendlyBrunchDinnerKid Friendly
This cozy spot features a dog-friendly patio with outdoor seating near a fountain, creating a relaxed vibe perfect for those seeking gluten-free options. The staff is known for being extremely flexible and accommodating, ensuring a comfortable dining experience for guests with dietary needs.
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30 W Broad St, Greenville, SC 29601, USA
Gluten Free IconAccommodating Gluten-Free
DinnerKnowledgeable StaffVegetarian OptionsAsianCocktailsSushiDeliveryTake Away
This spot impresses with its gorgeous, super open design and cherry blossom-inspired decor, creating a visually stunning setting. Staff are attentive to gluten-free needs, ensuring a safe and accommodating dining experience with dedicated gluten-free menus available.
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Dedicated gluten-free menu

4031 US-17 BUS, Murrells Inlet, SC 29576, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchOpen LateSeafoodCocktailsDeliveryTake Away
Perched with unbeatable water views of the marsh and harbor, this three-story ship-themed restaurant offers a relaxed atmosphere ideal for those with gluten sensitivities. The attentive service ensures all dietary needs are met, enhancing the comfortable, vacation vibe.
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Gluten-free options are marked

2213-B Middle St, Sullivan's Island, SC 29482, USA
Gluten-free options
BreakfastLunchDinnerBrunchCocktailsDeliveryTake AwayOutdoor Seating
This classy and cute venue offers a beautifully decorated space with a bright, fun atmosphere perfect for gluten-free diners. The staff is exceptionally knowledgeable and accommodating, ensuring a safe and enjoyable experience for those with gluten-free needs.
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823a Lady St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerMexicanCocktailsDeliveryTake AwayOutdoor SeatingBar
This spot offers a vibrant, cozy atmosphere enhanced by soft lighting and tea light candles, creating a welcoming setting for those seeking gluten-free options. Attentive service ensures guests with gluten allergies feel cared for and accommodated throughout their visit.
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Gluten-free options are not marked

4123 US-17 BUS Suite A, Murrells Inlet, SC 29576, USA
Gluten Free IconAccommodating Gluten-Free
Wine BarSushiSeafoodCocktailsAsianKid FriendlyOutdoor SeatingAmerican
Set by the water with a patio offering stunning inlet views, this spot features a serene outdoor bar where evening music enhances the inviting atmosphere. The relaxed waterfront setting provides a pleasant backdrop for those seeking a gluten-free dining experience, though menu availability may vary.
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Gluten-free options are marked

160 E Bay St, Charleston, SC 29401, USA
Gluten-free options
BreakfastLunchDinnerBrunchCafeCocktailsDeliveryTake Away
This intimate spot offers a charming and intimate atmosphere reminiscent of a Parisian street scene, with a lovingly decorated, très chic interior and impeccable, accommodating service that thoughtfully caters to gluten-free needs, ensuring a truly inviting experience.
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114 St Philip St A, Charleston, SC 29403, USA
Gluten-free options
CocktailsBrunchMediterraneanOpen Late NightOutdoor SeatingLunchDinnerTake Away
This quaint spot features a cozy outdoor patio and a warm brick interior with soft lighting, creating a relaxed and intimate atmosphere ideal for gluten-free diners seeking comfort and ambiance. The attentive service ensures a conscientious dining experience for those with gluten sensitivities.
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110 Park Ave SW, Aiken, SC 29801, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsBrunchBreakfastDinnerLunchCiderDessertsTacos
Set on a quiet street lined with magnolia trees, this spot offers a warm, inviting atmosphere ideal for those seeking gluten-free options. The outdoor sidewalk seating provides a relaxed setting, while the kind staff ensure attentive service, making it a fun spot for gluten-free brunch.
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1190 Farrow Pkwy, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
Allergen FriendlyAsianDairy Free OptionsDeliveryDinnerKid FriendlyOpen Late NightLunch
This spacious restaurant offers a cozy atmosphere with closely arranged tables that create an intimate dining experience. The attentive staff provide exceptional service, especially for guests with gluten allergies, ensuring a safe and welcoming environment for those seeking gluten-free accommodations.
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Gluten-free options are marked

78 N Market St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBakeryCafeCocktailsDeliveryTake AwayKid Friendly
This stylish, Southern-inspired cafe offers a fun atmosphere centered entirely on desserts with a buzzing bar-like vibe and fantastic music. It features gluten-free options, including cakes that provide a delightful choice for those seeking gluten-free desserts in a lively setting.
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630 King St, Charleston, SC 29403, USA
Gluten-free options
LunchDinnerBrunchOpen LateCocktailsDeliveryTake AwayPet Friendly
This spot offers a pleasant atmosphere with a relaxing patio, making it a welcoming haven for those seeking gluten-free options. The variety of gluten-free dishes and quick, fantastic service enhance the dining experience for guests with dietary needs.
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835 Savannah Hwy, Charleston, SC 29407, USA
Gluten-free options
BreakfastLunchBrunchAmericanCocktailsDeliveryTake AwayPet Friendly
This casual dining spot offers a family-friendly atmosphere perfect for both kids and adults. Known for its gluten-free menu options, it provides a welcoming setting with great service, making it a reliable choice for gluten-free brunch enthusiasts seeking a relaxed experience.
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9 Magnolia Rd, Charleston, SC 29407, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateSeafoodCocktailsDeliveryTake AwayPet Friendly
This spot features a relaxed, casual atmosphere with a pub-like feel, blending New England charm and southern hospitality. The long bar and ample seating create a welcoming setting, complemented by quick, attentive service and a notable gluten-free menu for diverse dietary needs.
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153b E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodCocktailsDinnerBread ItemsLunchDeliveryTake AwayOutdoor Seating
This spot offers a warm, eclectic atmosphere with a classy yet casual vibe and dim lighting that creates a buzzing bar ambiance. The knowledgeable staff provide attentive service, making it a welcoming choice for those seeking a gluten-free friendly environment.
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207 S Main St, Greenville, SC 29601, USA
Gluten Free IconAccommodating Gluten-Free
DinnerKid FriendlyOutdoor SeatingTake AwayCiderCocktailsBreakfastLunch
Set within a beautiful historic building, this restaurant offers a variety of seating options including roomy booths with pillows and a pet-friendly patio with umbrellas. The accommodating service ensures a comfortable experience for those with gluten-free needs.
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1315 Hwy 17 N, North Myrtle Beach, SC 29582, USA
Gluten-free options
LunchDinnerDeliveryTake AwayKid FriendlyCocktailsRestaurant
This steakhouse features a fancy yet casual atmosphere with a super clean interior and friendly, knowledgeable staff who handle gluten-free dietary needs with care. The setting is welcoming and accommodating, making it a great choice for those seeking a gluten-free dining experience.
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550 S Main St, Greenville, SC 29601, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchOpen LateAmericanCocktailsDeliveryTake Away
This elegant venue features gorgeous interiors with wall-to-ceiling windows offering stunning river views, creating a lively and contemporary atmosphere. Attentive service enhances the experience, making it a memorable choice for those seeking a gluten-free friendly setting.
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1214 Main St, Columbia, SC 29201, USA
Gluten-free options
CocktailsDeliveryTake AwayOutdoor SeatingBarRestaurant
This intimate spot offers a calm and sexy atmosphere with dark, earthy decor that enhances the dining experience. The lovely ambiance and attentive service ensure guests with gluten-free needs feel well cared for and comfortable throughout their visit.
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807 By Pass 123 #16, Seneca, SC 29678, USA
Gluten-free options
BreakfastLunchDinnerBrunchBakeryOpen LateCafeCocktails
This cozy café features repurposed church pews and a welcoming, calming ambience perfect for a gluten-free dining experience. With gluten-free, vegetarian, and vegan-friendly options crafted from locally grown ingredients, it’s an ideal spot for health-conscious guests seeking fresh, flavorful meals.
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209 E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchAmericanCocktailsDeliveryPet FriendlyOutdoor Seating
This vibrant spot offers a friendly, welcoming atmosphere with a trendy interior and lively energy from groups and live music. The attentive staff ensure a comfortable experience, and the gluten-free options are thoughtfully accommodated, making it ideal for those with dietary needs.
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7651 N Kings Hwy, Myrtle Beach, SC 29572, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsAmericanDeliveryDinnerKid FriendlyLunchOutdoor SeatingTake Away
This lively spot offers a welcoming atmosphere with live music and an inviting outdoor patio, perfect for those seeking a gluten-free friendly dining experience. The staff is knowledgeable and attentive, ensuring a safe and pleasant environment for guests with gluten allergies.
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101 S Kings Hwy, Myrtle Beach, SC 29577, USA
Gluten-free options
LunchDinnerOpen LateAmericanSeafoodCocktailsDeliveryTake Away
This lively spot offers a buzzing atmosphere with attentive service that ensures gluten-free needs are well accommodated. The host and staff are knowledgeable, highlighting gluten-free options clearly, making it a great choice for those seeking a safe and enjoyable dining experience.
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3421 Knoles St, Myrtle Beach, SC 29577, USA
Gluten-free options
CafeCocktailsRestaurant
This vibrant brewery features a spacious outdoor grassy area with a dog run and beer garden, ideal for larger group gatherings and families. Inside, a small kid play area and lively live music performances create a welcoming, fun atmosphere with friendly service and an amazing vibe.
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99 S Market St Suite 5, Charleston, SC 29401, USA
Gluten-free options
BreakfastLunchDinnerBrunchAmericanCocktailsDeliveryTake Away
This lively spot offers an astounding live music experience with a vibrant atmosphere and outside seating perfect for soaking in the vibe. The attentive, patient service ensures a welcoming environment, especially for guests with gluten allergies.
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2920 Hollywood Dr, Myrtle Beach, SC 29577, USA
Gluten-free options
LunchDinnerCocktailsDeliveryKid FriendlyRestaurant
This vibrant steakhouse offers a fast-paced dining experience with a lively atmosphere. Guests enjoy attentive service and a dynamic setting that complements the overall experience, making it a great choice for those seeking a gluten-free friendly environment.
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547 King St, Charleston, SC 29403, USA
Gluten-free options
LunchDinnerBrunchOpen LateCocktailsDeliveryPet FriendlyOutdoor Seating
This spot exudes a 1920s speakeasy vibe with vintage-inspired dark wood decor and a charming patio for outdoor seating. Notably, it offers exceptional accommodation for gluten-free and celiac diets, supported by attentive staff who ensure safe dining experiences.
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300 Technology Center Way Suite #203, Rock Hill, SC 29730, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchAmericanCocktailsDeliveryPet FriendlyOutdoor Seating
Charming restaurant with a quiet outdoor dining area offering limited but safe gluten-free options amid historic vibes.
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10 Windermere Blvd, Charleston, SC 29407, USA
Gluten-free options
LunchDinnerVeganOpen LateMexicanAmericanCocktailsDelivery
This intimate spot offers a welcoming vibe with a focus on healthy options for gluten-sensitive guests. The fresh and delicious experience is complemented by great prices, making it an accessible and inviting choice for those seeking gluten-free dining.
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22 E Court St, Greenville, SC 29601, USA
Gluten-free options
LunchDinnerDeliveryTake AwayRestaurantCocktailsOutdoor SeatingKid Friendly
This intimate spot buzzes with life, featuring walk-up seating and a cozy dining area that feels like a hidden gem. Guests enjoy the lively atmosphere and attentive service, making it a welcoming place for those seeking a gluten-free friendly environment with a focus on comfort and ambiance.
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20 N Main St, Greenville, SC 29601, USA
Gluten-free options
CocktailsDeliveryTake AwayBarRestaurant
This lively bar offers a cool, comfortable atmosphere blending a homie and tourist vibe, perfect for a relaxed gluten-free outing. The back houses a unique restaurant with a chef who provides expert guidance on gluten-free options, ensuring a safe and delicious experience.
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