Top 50 Gluten-Free Seafood Havens Across South Carolina

185 E Bay St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
SeafoodAmericanAllergen FriendlyBrunchDairy Free OptionsDinnerLunchVegan Options
This restaurant offers a warm, inviting atmosphere with three spacious rooms featuring unique art and rustic decor, creating a perfect setting for those seeking gluten-free dining. The staff is knowledgeable and attentive, ensuring a safe and enjoyable experience for guests with gluten allergies.
Menu
View menu
Dedicated gluten-free menu

4954 Hwy 17 S, North Myrtle Beach, SC 29582, USA
Gluten Free IconCeliac friendly
SeafoodAllergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingTake Away
Waterfront restaurant with dedicated gluten-free menu and manager-led allergy care ensuring safe, tasty meals.
Menu
View menu
Dedicated gluten-free menu

2 Hudson Rd, Hilton Head Island, SC 29926, USA
Gluten Free IconCeliac friendly
SeafoodAllergen FriendlyBrunchDairy Free OptionsDinnerPet FriendlyKid FriendlyLunch
Waterfront spot with large gluten-free menu and dedicated fryer for safe, celiac-friendly fried seafood.
Menu
View menu
Dedicated gluten-free menu

925 10th St, Port Royal, SC 29935, USA
Gluten Free IconCeliac friendly
SeafoodAllergen FriendlyDairy Free OptionsDinnerPet FriendlyKid FriendlyLunchOutdoor Seating
Cozy Southern seafood spot with an expansive gluten-free menu and allergen-aware staff ensuring safe, delicious dining.
Menu
View menu
Gluten-free options are marked

707 S Kings Hwy, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
DinnerItalianDeliveryTake AwayKid FriendlyLunchDairy FreePasta
This Italian eatery offers a classy yet cozy atmosphere with a personable accordion player enhancing the experience. It is extremely accommodating for gluten-free diners, featuring a full gluten-free menu and knowledgeable staff ensuring safe, delicious options for those with celiac disease.
Menu
View menu
Gluten-free options are marked

192 E Bay St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
DinnerLunchBreakfastDairy Free OptionsAllergen FriendlyBread ItemsDessertsSeafood
This venue offers a hip, intimate, and laid-back atmosphere with a beautifully designed interior that enhances the dining experience. The warm, welcoming vibe is elevated by live music from a talented singer and guitarist, making it an inviting spot for those seeking gluten-free dining with excellent service and accommodating staff.
Menu
View menu
Gluten-free options are not marked

8014 N Kings Hwy B, Myrtle Beach, SC 29572, USA
Gluten Free IconCeliac friendly
BreakfastLunchDinnerBrunchSeafoodDeliveryTake AwayOutdoor Seating
This visually stunning venue features jellyfish lights and an open kitchen with all-wood finishes, creating a unique and tasteful atmosphere. Guests with gluten sensitivities appreciate the knowledgeable, accommodating service and the thoughtful gluten-free options clearly labeled on the menu.
Menu
View menu
Gluten-free options are marked

38 Shelter Cove Ln, Hilton Head Island, SC 29928, USA
Gluten Free IconCeliac friendly
SeafoodDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingDedicated GF FryerBeer
Perched atop with breathtaking water views, this spot offers a lovely open-air atmosphere perfect for gluten-free diners. A dedicated fryer ensures safe fried seafood, blending upscale dining with casual comfort in a welcoming setting.
Menu
View menu
Dedicated gluten-free menu

504 Mill St, Mt Pleasant, SC 29464, USA
Gluten Free IconAccommodating Gluten-Free
SushiSeafoodAmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDinner
Perched atop a quaint rooftop with incredible views of the salt marsh and Shem Creek, this tavern offers a serene and comfortable atmosphere enhanced by fairy-lit ceilings and casual decor. The attentive staff ensures a safe and welcoming environment for gluten-free diners, making it a standout choice for those with gluten sensitivities.
Menu
View menu
Gluten-free options are marked

82 Queen St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
SeafoodDinnerLunchOutdoor SeatingAllergen FriendlyDessertsBrunchAmerican
Set in a charming historic setting, this large restaurant features a beautiful tucked-away courtyard offering an intimate yet elegant atmosphere. The gorgeous ambiance and attentive service make it a standout choice for those seeking gluten-free dining with care and consideration.
Menu
View menu
Gluten-free options are marked

320 Wingo Way #100, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
LunchDinnerBrunchAmericanSeafoodDeliveryTake AwayPet Friendly
This venue captivates with its rustic charm and low country coastal decor, creating an intimate yet inviting atmosphere ideal for gluten-free diners. The staff is attentive and knowledgeable, ensuring excellent gluten-free accommodations and a welcoming Southern ambiance.
Menu
View menu
Gluten-free options are marked

10 Hayne St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
DinnerSeafoodDairy FreeDessertsOpen LateDeliveryTake AwayKid Friendly
This seafood spot offers a warm, bustling atmosphere with dark wood-paneled interiors and comfy booths, creating an inviting setting. The attentive, accommodating staff ensure a seamless experience for gluten-free diners, supported by a dedicated gluten-free menu and thoughtful service.
Menu
View menu
Dedicated gluten-free menu

4097 US-17 BUS, Murrells Inlet, SC 29576, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodDinnerLunchAmericanTake AwayBeerCiderOpen Late
This waterfront spot features a spacious patio with open-air seating and plexiglass barriers, offering a breezy yet comfortable dining experience overlooking a serene inlet. Inside, a large saltwater aquarium creates a captivating ambiance, complemented by attentive, allergy-aware service ensuring a safe gluten-free visit.
Menu
View menu
Gluten-free options are marked

4744 US-17 S, North Myrtle Beach, SC 29582, USA
Gluten Free IconCeliac friendly
GrillSeafoodDinnerKid FriendlyOutdoor SeatingTake AwayBeerCider
Set on the Intracoastal with a beautiful mezzanine water view, this lively spot offers a spacious, upscale yet kid-friendly atmosphere. The attentive service and staff's deep knowledge ensure a safe, accommodating experience for gluten-free diners.
Menu
View menu
Gluten-free options are marked

31 J C Long Blvd, Isle of Palms, SC 29451, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodCocktailsAmericanBrunchBreakfastAllergen FriendlyDairy Free OptionsDinner
This spot offers a laid-back, family-friendly atmosphere with authentic Southern hospitality. The shaded, dog-friendly back patio enhances its welcoming charm, making it a comfortable choice for those seeking a gluten-free dining experience with attentive service and accommodating staff.
Menu
View menu
Gluten-free options are marked

205 E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchSeafoodDeliveryTake AwayOutdoor SeatingKid Friendly
This spot offers a comfortable atmosphere blending old saloon style with modern flair, featuring versatile seating including high tops by windows with lovely views. The attentive service shows genuine care for gluten-free needs, making it a welcoming choice for gluten-sensitive diners.
Menu
View menu
Gluten-free options are marked

4911 US-17 BUS, Murrells Inlet, SC 29576, USA
Gluten Free IconCeliac friendly
LunchDinnerAllergen FriendlyDairy FreeCiderKid FriendlyOutdoor SeatingOpen Late
This spot offers a relaxed atmosphere with a night-time vibe, enhanced by a tiki bar and live music including a charming spoon player. Guests enjoy great views from the porch and marsh walkway, creating memorable moments in a welcoming setting for those seeking a safe gluten-free experience.
Menu
View menu
Dedicated gluten-free menu

101 Marshland Rd, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodDinnerLunchOutdoor SeatingBrunchDeliveryTake AwayPet Friendly
Set in a beautifully designed space with southern charm and warm hospitality, this bustling restaurant offers spectacular waterfront and marsh views from every table. The gluten-free menu is extensive and clearly marked, ensuring a welcoming experience for those with gluten sensitivities.
Menu
View menu
Gluten-free options are marked

5070 International Blvd, North Charleston, SC 29418, USA
Gluten Free IconCeliac friendly
PokeAsianSushiSeafoodDairy Free OptionsDeliveryDinnerLunch
This bright, friendly spot offers a clean, minimalist setting ideal for gluten-free diners. The staff is knowledgeable about gluten-free options, ensuring a safe, satisfying experience with clearly labeled choices and friendly, fast service.
Menu
View menu
Gluten-free options are marked

1024 William Hilton Pkwy, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSeafoodDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
This clean, bright spot offers a welcoming atmosphere with attentive staff who go above and beyond to accommodate gluten-free needs. Their careful preparation and separate frying methods ensure a safe, enjoyable dining experience for those with gluten sensitivities.
Menu
View menu
Gluten-free options are marked

5041 International Blvd, North Charleston, SC 29418, USA
Gluten Free IconCeliac friendly
Wine BarGrillSeafoodAmericanBrunchDinnerKid FriendlyOpen Late Night
This stylish and classy restaurant offers a chill atmosphere with a lively bar area, creating a vibrant vibe. Known for being accommodating for gluten allergies, it provides gluten-free menu options and knowledgeable service that ensures a comfortable dining experience for those with gluten restrictions.
Menu
View menu
Dedicated gluten-free menu

193 King St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSeafoodDeliveryTake AwayKid FriendlyRestaurant
This intimate spot offers a perfect mix of an intimate little bar and a hip club ambiance, enhanced by nautical chic decor and live plants. The staff is welcoming and attentive, ensuring a safe and accommodating experience for gluten-free guests.
Menu
View menu

232 S Sea Pines Dr, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodAllergen FriendlyCoffeeDinnerKid FriendlyLunchOutdoor SeatingTake Away
Set on the waterfront, this lively spot offers a vibrant atmosphere with a large outdoor bar and deck featuring live music and marina views. The spacious lawn invites fun games, while colorful Scarlet Macaws nearby provide a unique wildlife experience, making it an engaging destination for those seeking a gluten-free friendly setting with attentive service and a memorable ambiance.
Menu
View menu

1401 29th Ave N, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodAllergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchDeliveryTake Away
This upscale seafood spot features a fun and classy nautical décor with a well-organized layout that accommodates families and large parties comfortably. The staff and management go above and beyond to ensure a gluten-free and allergy-friendly experience, offering custom-made dishes and clear food labeling in a clean, inviting atmosphere.
Menu
View menu
Dedicated gluten-free menu

106 Parkway Ave, Summerville, SC 29483, USA
Gluten Free IconCeliac friendly
SushiAsianDairy Free OptionsDinnerKid FriendlyLunchSeafoodAmerican
Japanese steakhouse with gluten-free menu and careful preparation amid a starry night sky mural.
Menu
View menu

1517 Palm Blvd suite a, Isle of Palms, SC 29451, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodLunchBrunchBreakfastPet FriendlyOutdoor SeatingBread ItemsBurgers
This contemporary spot offers a quiet, peaceful atmosphere with a nicely decorated, quaint, and modern environment. Known for being gluten-free friendly, it provides a welcoming setting where service is amazing and locals are very friendly, making it a hidden gem for gluten-free diners.
Menu
View menu

109 W Stone Ave, Greenville, SC 29609, USA
Gluten Free IconCeliac friendly
GrillSeafoodAllergen FriendlyDairy Free OptionsDeliveryDinnerKid FriendlyLunch
Menu
View menu
Dedicated gluten-free menu

1 Hudson Rd, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchAmericanSeafoodDeliveryTake AwayOutdoor Seating
Perched on the water with stunning waterfront views, this lively spot offers a comfortable outdoor seating area with shade and fans, perfect for enjoying a meal in a scenic, breezy setting. The family-owned atmosphere is welcoming and accommodating, especially for gluten-free diners seeking a relaxed yet vibrant dining experience.
Menu
View menu

87 N Sea Pines Dr, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchSeafoodDeliveryTake AwayPet FriendlyOutdoor Seating
Set against a stunning beach backdrop, this spot offers a vibrant atmosphere with live music and breezy oceanfront views. The attentive service ensures a welcoming experience, especially for guests with gluten allergies, making it a gluten-free friendly destination with personalized accommodations.
Menu
View menu
Gluten-free options are marked

112 N Main St, Anderson, SC 29621, USA
Gluten Free IconAccommodating Gluten-Free
Wine BarSeafoodCocktailsAmericanAllergen FriendlyBrunchDinnerKid Friendly
This cozy spot features a dog-friendly patio with outdoor seating near a fountain, creating a relaxed vibe perfect for those seeking gluten-free options. The staff is known for being extremely flexible and accommodating, ensuring a comfortable dining experience for guests with dietary needs.
Menu
View menu

215 Meeting St, Charleston, SC 29401, USA
Gluten-free options
SeafoodBreakfastLunchDinnerBrunchOpen LateDeliveryTake Away
This family-owned seafood spot offers a warm, laid-back atmosphere enriched by plaques honoring celebrity guests, creating a charming and inviting vibe. It provides clearly labeled gluten-free options and a gluten-free menu to accommodate dietary needs, making it a notable choice for gluten-free diners seeking a welcoming setting.
Menu
View menu

807 William Hilton Pkwy #1000, Hilton Head Island, SC 29928, USA
Gluten-free options
LunchDinnerBrunchSeafoodDeliveryTake AwayKid FriendlyBreakfast
This eatery offers a quiet, cozy atmosphere with a warm, inviting service that is especially accommodating to gluten-free diners. The staff's knowledge and friendliness ensure a comfortable experience, complemented by clean, comfortable outdoor seating even in rain.
Menu
View menu
Gluten-free options are marked

4031 US-17 BUS, Murrells Inlet, SC 29576, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchOpen LateSeafoodCocktailsDeliveryTake Away
Perched with unbeatable water views of the marsh and harbor, this three-story ship-themed restaurant offers a relaxed atmosphere ideal for those with gluten sensitivities. The attentive service ensures all dietary needs are met, enhancing the comfortable, vacation vibe.
Menu
View menu
Gluten-free options are marked

6307 N Kings Hwy A, Myrtle Beach, SC 29572, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSeafoodDeliveryPet FriendlyOutdoor SeatingKid Friendly
This seafood spot offers a casual, welcoming vibe with an authentic atmosphere that makes dining comfortable. The friendly, attentive service ensures guests feel cared for, especially those with gluten-free needs, enhancing the overall experience.
Menu
View menu

1081 Morrison Dr, Charleston, SC 29403, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodBrunchDinnerLunchOutdoor SeatingTake AwayBread ItemsDesserts
Spacious venue with phenomenal gluten-free bread and an outstanding celiac-friendly menu.
Menu
View menu

8173 Charlotte Hwy, Fort Mill, SC 29707, USA
Gluten Free IconCeliac friendly
Salad BarSushiAsianDinnerLunchSeafoodTake AwayVegetarian Options
This bright, very clean spot offers a welcoming atmosphere with attentive, friendly staff who ensure a perfect dining experience. The clearly marked gluten-free options and fresh, vibrant ingredients make it a must-try for those with dietary restrictions seeking quality and variety.
Menu
View menu
Dedicated gluten-free menu

1513 Main St, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
DeliveryDinnerKid FriendlyOpen Late NightSeafoodLunchTake AwayOutdoor Seating
This spot offers a warm, inviting atmosphere blending classy and modern elements, perfect for those seeking gluten-free dining. The exceptional service is attentive and patient with dietary needs, making it a go-to place for gluten-friendly options and memorable experiences.
Menu
View menu

397 Squire Pope Rd, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
SushiSeafoodDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingDesserts
Perched on the water, this spot features a large patio with beautiful waterfront views and varied seating, including large chairs perfect for relaxing. The dog-friendly outdoor bar and lively atmosphere with live music create a welcoming setting ideal for gluten-free diners seeking ambiance and attentive service.
Menu
View menu
Dedicated gluten-free menu

4830 O'Hear Ave, North Charleston, SC 29405, USA
Gluten Free IconCeliac friendly
LunchDinnerBrunchOpen LateSeafoodDeliveryTake AwayOutdoor Seating
This spot offers a casual, lively atmosphere with outdoor picnic tables and live music, creating an inviting setting for those seeking gluten-free dining. The staff is knowledgeable and attentive, ensuring a safe and enjoyable experience for guests with gluten sensitivities.
Menu
View menu
Dedicated gluten-free menu

1306 N Ocean Blvd, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSeafoodDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
Perched on the water with breathtaking ocean views, this spot offers a welcoming, relaxing atmosphere ideal for those seeking a gluten-free dining experience. The staff is notably accommodating, ensuring allergy-friendly service in a serene setting.
Menu
View menu

3005 Maybank Hwy, Johns Island, SC 29455, USA
Gluten Free IconAccommodating Gluten-Free
Take AwayDairy Free OptionsSeafoodLunchDinnerDeliveryKid FriendlyBar
This restaurant features a modern, attractive ambiance with light, airy decor and simple yet elegant table settings, offering a comfortable setting. However, gluten-free diners may find the experience challenging due to reported lack of attention to gluten-free needs and slow, dismissive service.
Menu
View menu

4269 Luck Ave, Little River, SC 29566, USA
Gluten-free options
Wine BarDinnerSeafoodDeliveryTake AwayFrenchOutdoor SeatingKid Friendly
Charming Victorian setting with a clearly marked gluten-free menu and attentive, knowledgeable staff.
Menu
View menu

145 Jungle Rd, Edisto Island, SC 29438, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchAmericanSeafoodDeliveryTake Away
This quaint eatery offers a comfortably casual atmosphere with both covered and uncovered dog-friendly outdoor seating. Its cozy vibe and friendly ambiance make it a welcoming spot for those seeking gluten-free dining options in a lively, beach-inspired setting.
Menu
View menu

4123 US-17 BUS Suite A, Murrells Inlet, SC 29576, USA
Gluten Free IconAccommodating Gluten-Free
Wine BarSushiSeafoodCocktailsAsianKid FriendlyOutdoor SeatingAmerican
Set by the water with a patio offering stunning inlet views, this spot features a serene outdoor bar where evening music enhances the inviting atmosphere. The relaxed waterfront setting provides a pleasant backdrop for those seeking a gluten-free dining experience, though menu availability may vary.
Menu
View menu
Gluten-free options are marked

104 William Hilton Pkwy, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodAllergen FriendlyDinnerKid FriendlyLunchOutdoor SeatingVegan OptionsVegetarian Options
Bright interior with gluten-free options clearly noted and knowledgeable staff ensuring safe meals.
Menu
View menu

1407 Shrimp Boat Ln, Mt Pleasant, SC 29464, USA
Gluten-free options
SeafoodBrunchDairy Free OptionsDinnerPet FriendlyOpen Late NightOutdoor SeatingTake Away
Perched on the water with gorgeous harbor views, this spot offers a relaxing atmosphere enhanced by sights of kayaks and dolphins. The friendly, accommodating staff ensure a welcoming experience for those seeking a gluten-free dining environment.
Menu
View menu

4708 Forest Dr, Columbia, SC 29206, USA
Gluten Free IconCeliac friendly
Wine BarGrillSeafoodAmericanBrunchDinnerKid FriendlyOpen Late Night
This seafood spot offers a peaceful and inviting atmosphere with a quiet dining room that enhances the cozy experience. The attentive service ensures that gluten-free diners feel well cared for, making it a reliable choice for gluten-free guests.
Menu
View menu
Dedicated gluten-free menu

32 River Landing Dr, Charleston, SC 29492, USA
Gluten Free IconCeliac friendly
LunchDinnerAllergen FriendlyVegetarianDairy FreeOutdoor SeatingBrunchSeafood
Perched with stunning waterfront views, this spot offers a beautifully decorated dining room and rooftop outdoor seating overlooking the Cooper River. The attentive service ensures gluten-free accommodations are handled with care, creating a welcoming atmosphere for those with dietary needs.
Menu
View menu
Gluten-free options are not marked

1515 Palm Blvd suite a, Isle of Palms, SC 29451, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchSeafoodDeliveryTake AwayPet FriendlyOutdoor Seating
This intimate, upscale spot features an upbeat atmosphere perfect for quiet conversation and impressive decor that delights upon entry. The staff is exceptional and attentive, ensuring a supportive experience for guests with gluten-free needs.
Menu
View menu
Dedicated gluten-free menu

8703 US Highway 17 Bypass South, Myrtle Beach, SC 29575, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchSeafoodDeliveryTake AwayKid Friendly
Upscale seafood spot with a gluten-free menu and a sophisticated ambiance for dining.
Menu
View menu
Dedicated gluten-free menu

© 2025 Atly - Your Local Guide to Gluten-Free Dining