Top 50 Gluten-Free American Diners Across South Carolina

1875 N Hwy 17, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
DinnerLunchDairy Free OptionsAllergen FriendlyKnowledgeable StaffDedicated GF FryerSeparate GF MenuAmerican
This upscale spot offers a warm, inviting atmosphere ideal for relaxed dining or special occasions, with a dog-friendly patio and multiple TVs for sports fans. Its attentive, friendly staff and commitment to gluten-free dining create a confident, enjoyable experience for those with gluten sensitivities.
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82 Wentworth St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
GF MenuDedicated GF FryerAllergen FriendlyBreakfastLunchDinnerCocktailsCasual
This hip, upscale spot features a bright, beachy decor and a cool outdoor courtyard, creating a lively yet charming atmosphere. With a dedicated gluten-free fryer and allergy-aware service, it’s perfect for those seeking safe, gluten-free dining in a welcoming setting.
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1 N Forest Beach Dr j, Hilton Head Island, SC 29928, USA
Gluten Free IconCeliac friendly
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayPet Friendly
This spacious eatery offers a dedicated gluten-free experience with green plates and separate fryers ensuring allergy safety. The dog-friendly outdoor patio complements the homey vibe, enhanced by uplifting Christian and gospel music, making it a welcoming spot for gluten-sensitive guests.
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185 E Bay St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
SeafoodAmericanAllergen FriendlyBrunchDairy Free OptionsDinnerLunchVegan Options
This restaurant offers a warm, inviting atmosphere with three spacious rooms featuring unique art and rustic decor, creating a perfect setting for those seeking gluten-free dining. The staff is knowledgeable and attentive, ensuring a safe and enjoyable experience for guests with gluten allergies.
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4205 N Kings Hwy, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
BrunchBreakfastAllergen FriendlyDairy Free OptionsKid FriendlyLunchTake AwayBeer
This cozy spot offers a warm, inviting atmosphere reminiscent of a small Parisian bistro, with unique couch-like seating and tasteful decor. Soft acoustic guitar music enhances the experience, making it a perfect setting for gluten-free dining with diverse, safe options.
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711 Gervais St, Columbia, SC 29201, USA
Gluten Free IconCeliac friendly
GrillBurgersCocktailsAmericanAllergen FriendlyDairy Free OptionsDeliveryDinner
This spacious spot offers a pet-friendly porch and a lively bar with numerous TVs, creating a vibrant atmosphere. It stands out as a gluten-free haven with a dedicated fryer and a wide variety of tasty gluten-free options, ensuring a safe and enjoyable dining experience.
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860 S Church St, Greenville, SC 29601, USA
Gluten Free IconAccommodating Gluten-Free
AmericanVegan OptionsAllergen FriendlyBrunchCoffeeDairy Free OptionsLunchTake Away
This charming farmhouse-style eatery offers a happy, caring atmosphere with a dog-friendly outdoor seating area and 90s country tunes, creating a comfortable and inviting environment ideal for those seeking gluten-free options in a welcoming setting.
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214 N Cedar St, Summerville, SC 29483, USA
Gluten Free IconCeliac friendly
AmericanBrunchAllergen FriendlyCoffeeKid FriendlyLunchOutdoor SeatingTake Away
Set in a charming upcycled old home with southern chic decor and inviting porches, this cozy cafe offers a dog-friendly outdoor patio and a sunroom with a great aesthetic. The friendly staff and clean, modern atmosphere create a welcoming space ideal for gluten-free diners.
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464 N Nassau St, Charleston, SC 29403, USA
Gluten Free IconCeliac friendly
Knowledgeable StaffDinnerDairy Free OptionsTake AwayLunchAmericanDedicated GF Kitchen SpaceAllergen Friendly
This barbecue spot offers a shady outdoor seating area with picnic tables ideal for dog owners and a sizable indoor bar for a relaxed atmosphere. The staff's meticulous allergy protocols ensure a safe, welcoming environment for gluten-free diners, making it a standout choice for those with gluten sensitivities.
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1055 Johnnie Dodds Blvd #100, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
AmericanBrunchCoffeeDeliveryKid FriendlyLunchOutdoor SeatingTake Away
Charming café with extensive gluten-free options and a cozy, California vibey atmosphere.
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7931 N Kings Hwy #140, Myrtle Beach, SC 29572, USA
Gluten Free IconAccommodating Gluten-Free
GrillBurgersBreakfastAllergen FriendlyBrunchCoffeeKid FriendlyLunch
This charming brunch spot features a lively, warm atmosphere and a comfortable patio with shade and fans, creating an inviting setting for those seeking gluten-free dining. Attentive service enhances the experience, making it a standout choice for gluten-free guests.
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Broadway at the Beach, 1318 Celebrity Cir, Myrtle Beach, SC 29577, USA
Gluten Free IconCeliac friendly
AmericanAllergen FriendlyDairy Free OptionsDeliveryDinnerKid FriendlyLunchOutdoor Seating
Set inside a pyramid-shaped building filled with extensive memorabilia, this venue offers an upbeat, family-friendly atmosphere. The staff's exceptional care and attention ensure a safe, comfortable experience for gluten-free guests, with dedicated preparation areas enhancing confidence and enjoyment.
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4856 US-17, North Myrtle Beach, SC 29582, USA
Gluten Free IconAccommodating Gluten-Free
Wine BarLunchBrunchBreakfastVegan OptionsAllergen FriendlyDinnerKid Friendly
Set against a beautiful lake backdrop, this spacious eatery features a delightful patio with roll-down shades, fans, and misters, creating a comfortable outdoor dining experience. The gorgeous decor with purposeful beams and angles complements a vibrant atmosphere, making it an ideal spot for those seeking gluten-free dining in a welcoming setting.
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504 Mill St, Mt Pleasant, SC 29464, USA
Gluten Free IconAccommodating Gluten-Free
SushiSeafoodAmericanBrunchAllergen FriendlyBreakfastDairy Free OptionsDinner
Perched atop a quaint rooftop with incredible views of the salt marsh and Shem Creek, this tavern offers a serene and comfortable atmosphere enhanced by fairy-lit ceilings and casual decor. The attentive staff ensures a safe and welcoming environment for gluten-free diners, making it a standout choice for those with gluten sensitivities.
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887 Gold Hill Rd, Fort Mill, SC 29708, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerAmericanDeliveryTake AwayOutdoor SeatingKid Friendly
This modern burger spot offers a dedicated gluten-free menu with separate fryers and buns, ensuring a safe and delicious experience. The clean, well-maintained space and friendly, knowledgeable service create a welcoming atmosphere for gluten-sensitive diners.
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1218 N Retail Ct, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateAmericanDeliveryTake AwayKid FriendlyBar
This welcoming spot is celiac-friendly with a dedicated gluten-free fryer and separately served gluten-free buns to minimize cross-contamination. The friendly, attentive staff ensure a safe and comfortable dining experience for gluten-sensitive guests.
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Gluten-free options are marked

225 Calhoun St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
Allergen FriendlyDairy Free OptionsDeliveryKid FriendlyLunchOutdoor SeatingTake AwayVegan Options
Step into a cozy spot bursting with 80s and 90s memorabilia, creating a nostalgic museum vibe. The laid-back, inviting atmosphere and friendly, knowledgeable service make it a great choice for those seeking gluten-free dining in a charming, character-filled setting.
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Gluten-free options are not marked

4012 Deville St, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
AmericanBreakfastBrunchCoffeeFrenchLunchOutdoor SeatingWaffles / Crepes
This cafe offers a cozy yet lively atmosphere with an open floor plan and outdoor patio, enhanced by live acoustic guitar music. The French-inspired decor and full bar create a unique, inviting setting ideal for those seeking gluten-free dining options in a charming environment.
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30 Orchard Park Dr Suite 7, Greenville, SC 29615, USA
Gluten Free IconCeliac friendly
GrillDairy Free OptionsDinnerOpen Late NightLunchTake AwayDedicated GF FryerBread Items
This lively spot offers a dedicated gluten-free menu with separate fryers ensuring safe, flavorful options. The fun atmosphere features pool tables, darts, board games, and multiple TVs, making it a gluten-friendly haven for groups and families alike.
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6 Marina Side Dr, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchOpen LateAmericanDeliveryTake Away
This diner offers a fun, authentic throwback atmosphere with oldies music that enhances the dining experience. Known for its wide variety of gluten-free options, it provides a welcoming setting with friendly, knowledgeable staff attentive to gluten-free needs, making it a reliable choice for those seeking safe and enjoyable gluten-free dining.
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82 Queen St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
SeafoodDinnerLunchOutdoor SeatingAllergen FriendlyDessertsBrunchAmerican
Set in a charming historic setting, this large restaurant features a beautiful tucked-away courtyard offering an intimate yet elegant atmosphere. The gorgeous ambiance and attentive service make it a standout choice for those seeking gluten-free dining with care and consideration.
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3042 Howard Ave, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastBrunchCoffeeDairy Free OptionsKid FriendlyLunchOutdoor SeatingTake Away
This charming, southern-style restaurant features a warm, inviting atmosphere with a unique ceiling display and a lovely patio. Guests appreciate the friendly, welcoming staff and the clean, cozy setting, making it a great choice for those seeking gluten-free dining options.
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4097 US-17 BUS, Murrells Inlet, SC 29576, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodDinnerLunchAmericanTake AwayBeerCiderOpen Late
This waterfront spot features a spacious patio with open-air seating and plexiglass barriers, offering a breezy yet comfortable dining experience overlooking a serene inlet. Inside, a large saltwater aquarium creates a captivating ambiance, complemented by attentive, allergy-aware service ensuring a safe gluten-free visit.
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76 Queen St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchAmericanDeliveryTake AwayOutdoor SeatingBar
Set in a beautifully repurposed old house, this spot offers a peaceful upstairs patio perfect for a romantic, relaxed dining experience. The attentive, knowledgeable service ensures guests with gluten sensitivities feel safe and well cared for throughout their visit.
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Gluten-free options are not marked

435 William Hilton Pkwy suite g, Hilton Head Island, SC 29926, USA
Gluten Free IconCeliac friendly
BrunchLunchDinnerBreakfastBread ItemsSandwichesDessertsFries
This inviting spot offers a casual, friendly setting with a mom and pop diner vibe and a cute ice cream parlor atmosphere. Known for its extensive, clearly marked gluten-free options, it provides confident dining for those with gluten sensitivities alongside friendly, accommodating service.
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1025 Woodruff Rd, Greenville, SC 29607, USA
Gluten Free IconAccommodating Gluten-Free
LunchBrunchBreakfastCoffeeKid FriendlyBread ItemsPancakesAmerican
This cafe offers a warm, down-to-earth atmosphere reminiscent of a home kitchen, making it a comforting spot for those seeking gluten-free options. The variety of gluten-free pancakes and attentive service create a welcoming experience for guests with dietary needs.
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320 Wingo Way #100, Mt Pleasant, SC 29464, USA
Gluten Free IconCeliac friendly
LunchDinnerBrunchAmericanSeafoodDeliveryTake AwayPet Friendly
This venue captivates with its rustic charm and low country coastal decor, creating an intimate yet inviting atmosphere ideal for gluten-free diners. The staff is attentive and knowledgeable, ensuring excellent gluten-free accommodations and a welcoming Southern ambiance.
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2901a Devine St, Columbia, SC 29205, USA
Gluten Free IconCeliac friendly
MexicanCocktailsAllergen FriendlyBrunchDinnerKid FriendlyLunchOutdoor Seating
This modern eatery offers a relaxed, chill atmosphere with a pleasant outdoor dining area, making it an inviting spot for those seeking gluten-free options. The staff is knowledgeable and conscientious, ensuring a safe and enjoyable experience for gluten-sensitive guests.
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1 N Forest Beach Dr, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
AmericanAllergen FriendlyCoffeeKid FriendlyLunchOutdoor SeatingTake AwayVegetarian Options
This lively spot offers a fun, laid-back atmosphere with live music and comfortable seating, creating a welcoming environment. The staff is knowledgeable and accommodating about gluten-free needs, ensuring a safe and enjoyable experience for those with dietary restrictions.
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Gluten-free options are marked

4600 Devine St Suite C, Columbia, SC 29205, USA
Gluten Free IconCeliac friendly
BrunchBreakfastCoffeeKid FriendlyLunchOutdoor SeatingTake AwayVegan Options
This lively cafe offers a welcoming, homey vibe with attentive service that ensures a comfortable experience. Known for its exceptional gluten-free pancakes and a varied gluten-free menu, it stands out as a gluten-friendly brunch destination praised by many for its care and quality.
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Broadway at the Beach, 1114 Celebrity Cir, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
Allergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingTake AwayVegan Options
This spot features a friendly, inviting vibe with an amazing ambiance enhanced by a karaoke band and shows every thirty minutes, creating a lively atmosphere. The staff is notably accommodating for gluten allergies, ensuring a comfortable experience for gluten-free diners.
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65 Windermere Blvd, Charleston, SC 29407, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchBrunchCafeDeliveryTake AwayOutdoor SeatingKid Friendly
This charming cafe offers a cute, cozy cottage-core vibe with art-adorned walls and vine-covered exteriors, creating a welcoming atmosphere. Its roomy patio and dog-friendly outdoor space enhance the inviting setting, making it a delightful spot for those seeking gluten-free options in a relaxed environment.
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31 J C Long Blvd, Isle of Palms, SC 29451, USA
Gluten Free IconAccommodating Gluten-Free
SeafoodCocktailsAmericanBrunchBreakfastAllergen FriendlyDairy Free OptionsDinner
This spot offers a laid-back, family-friendly atmosphere with authentic Southern hospitality. The shaded, dog-friendly back patio enhances its welcoming charm, making it a comfortable choice for those seeking a gluten-free dining experience with attentive service and accommodating staff.
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1007 Tiger Blvd, Clemson, SC 29631, USA
Gluten Free IconAccommodating Gluten-Free
PizzaVegan OptionsDairy Free OptionsKid FriendlyLunchTake AwayVegetarian OptionsDinner
This vibrant spot offers a fun, college-town atmosphere with creative metal pedestals and a sunroom setting. The staff is knowledgeable about gluten-free options and ensures careful cross-contamination prevention, making it a welcoming place for those with gluten sensitivities.
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199 E Bay St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
DinnerBrunchAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
This establishment offers a gorgeous ambiance with Southern charm and live acoustic music, creating an elegant, movie-like atmosphere. The fantastic service ensures a safe and enjoyable experience for those with gluten intolerance, making it a gluten-free haven.
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32 Palmetto Bay Rd Suite 4A, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayOutdoor Seating
This spot offers a laid-back, island-style atmosphere with a quirky beach vibe and plentiful outdoor seating. The garden dining room provides a relaxed setting, while the staff is known for being knowledgeable and attentive to gluten-free needs, enhancing the overall experience.
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Gluten-free options are marked

4840 Forest Dr, Columbia, SC 29206, USA
Gluten Free IconCeliac friendly
BreakfastLunchDinnerBrunchAmericanCocktailsDeliveryTake Away
This spot features an upbeat and inviting atmosphere with an excellent gluten-free selection clearly marked for celiac diners. The knowledgeable service and diverse options ensure a satisfying experience for those seeking gluten-free meals.
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4726 Spruill Ave, North Charleston, SC 29405, USA
Gluten Free IconAccommodating Gluten-Free
BurgersAmericanDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingTake Away
Cozy spot with gluten-free buns and diverse patties, plus creative milkshakes.
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1301 Main St, Columbia, SC 29201, USA
Gluten Free IconAccommodating Gluten-Free
MexicanCocktailsDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingVegan Options
This lively spot offers a fun and energetic atmosphere with plenty of bar seating and TVs for sports fans, plus an inviting outdoor space. It stands out for its clearly marked gluten-free options and attentive service, making it a stress-free choice for gluten-free diners.
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Gluten-free options are marked

1125 Woodruff Rd, Greenville, SC 29607, USA
Gluten Free IconAccommodating Gluten-Free
GrillBurgersAmericanAllergen FriendlyBrunchDairy Free OptionsDinnerKid Friendly
This welcoming spot features diverse seating options including indoor, bar, and outdoor areas, making it ideal for groups. It is known for its dedicated gluten-free menu and attentive service, ensuring a safe and enjoyable dining experience for those with gluten allergies.
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Gluten-free options are marked

120 King St, Charleston, SC 29401, USA
Gluten Free IconCeliac friendly
BrunchBreakfastLunchAmericanBread ItemsDinnerDeliveryTake Away
This charming spot offers a fun diner aesthetic and a family-friendly atmosphere welcoming all ages. Known for its gluten-free bread and accommodating service, it ensures a safe and enjoyable experience for those with gluten sensitivities.
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Gluten-free options are not marked

1034B Woodruff Rd, Greenville, SC 29607, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerOpen LateMexicanAmericanDeliveryTake AwayOutdoor Seating
This vibrant spot offers a fun, energetic ambiance with bright, friendly 1950s Mexican-inspired decor. Known for excellent gluten-free accommodations, it provides a clean, upbeat setting where guests with gluten allergies feel confidently cared for and welcomed.
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Gluten-free options are not marked

5041 International Blvd, North Charleston, SC 29418, USA
Gluten Free IconCeliac friendly
Wine BarGrillSeafoodAmericanBrunchDinnerKid FriendlyOpen Late Night
This stylish and classy restaurant offers a chill atmosphere with a lively bar area, creating a vibrant vibe. Known for being accommodating for gluten allergies, it provides gluten-free menu options and knowledgeable service that ensures a comfortable dining experience for those with gluten restrictions.
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2461 Coastal Grand Cir, Myrtle Beach, SC 29577, USA
Gluten Free IconAccommodating Gluten-Free
Ice CreamAllergen FriendlyDairy Free OptionsKid FriendlyTake AwayVegan OptionsVegetarian OptionsDesserts
This lively spot offers a playful decor and fun photo booth areas, creating an inviting atmosphere perfect for gluten-free guests. With clearly marked gluten-free options and a separate production line for allergies, it ensures a safe, enjoyable experience for those with dietary restrictions.
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Francis Marion Hotel, 387 King St, Charleston, SC 29403, USA
Gluten Free IconAccommodating Gluten-Free
AmericanBreakfastDinnerLunchBrunchDeliveryTake AwayKid Friendly
This elegant yet simple spot offers a relaxing atmosphere with a live pianist enhancing the experience. Guests appreciate the clearly marked gluten-free options and attentive service, making it a top choice for gluten-free dining with a lovely park and fountain view.
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1024 William Hilton Pkwy, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerSeafoodDeliveryTake AwayPet FriendlyOutdoor SeatingKid Friendly
This clean, bright spot offers a welcoming atmosphere with attentive staff who go above and beyond to accommodate gluten-free needs. Their careful preparation and separate frying methods ensure a safe, enjoyable dining experience for those with gluten sensitivities.
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Gluten-free options are marked

1 Hudson Rd, Hilton Head Island, SC 29926, USA
Gluten Free IconAccommodating Gluten-Free
LunchDinnerBrunchAmericanSeafoodDeliveryTake AwayOutdoor Seating
Perched on the water with stunning waterfront views, this lively spot offers a comfortable outdoor seating area with shade and fans, perfect for enjoying a meal in a scenic, breezy setting. The family-owned atmosphere is welcoming and accommodating, especially for gluten-free diners seeking a relaxed yet vibrant dining experience.
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100 N Sea Pines Dr, Hilton Head Island, SC 29928, USA
Gluten Free IconAccommodating Gluten-Free
BreakfastLunchDinnerBrunchAmericanDeliveryTake AwayOutdoor Seating
Tranquil tavern with gluten-free options and separate fryers ensuring safe, delicious meals.
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Gluten-free options are marked

1609 Laurens Rd, Greenville, SC 29607, USA
Gluten Free IconAccommodating Gluten-Free
PizzaAmericanDinnerKid FriendlyLunchOutdoor SeatingTake AwayVegetarian Options
This small restaurant offers a lovely, fun, and comfortable atmosphere that welcomes guests with dietary restrictions. Its commitment to accommodating gluten-free diets is evident in the variety of options and knowledgeable, polite service that enhances the dining experience.
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171 E Bay St, Charleston, SC 29401, USA
Gluten Free IconAccommodating Gluten-Free
CocktailsBrunchBreakfastKid FriendlyOutdoor SeatingTake AwayBread ItemsSandwiches
This lively spot features a spacious dining area with indoor and outdoor seating, creating a welcoming atmosphere enhanced by pleasant music. Known for its full gluten-free menu and excellent service, it offers a fun and accommodating environment for gluten-free diners.
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